[HTML][HTML] Conjunctival melanoma: New insights in tumour genetics and immunology, leading to new therapeutic options

NJ Brouwer, RM Verdijk, S Heegaard… - Progress in Retinal and …, 2022 - Elsevier
Recent developments in oncology have led to a better molecular and cellular understanding
of cancer, and the introduction of novel therapies. Conjunctival melanoma (CoM) is a rare …

The role of major histocompatibility complex in organ transplantation-donor specific anti-major histocompatibility complex antibodies analysis goes to the next stage

T Nakamura, T Shirouzu, K Nakata… - International journal of …, 2019 - mdpi.com
Organ transplantation has progressed with the comprehension of the major
histocompatibility complex (MHC). It is true that the outcome of organ transplantation largely …

[HTML][HTML] A tubular EHD1‐containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane

S Caplan, N Naslavsky, LM Hartnell, R Lodge… - The EMBO …, 2002 - embopress.org
The Eps15 homology (EH) domain‐containing protein, EHD1, has recently been ascribed a
role in the recycling of receptors internalized by clathrin‐mediated endocytosis. A subset of …

Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma

AM Mehta, ES Jordanova, GG Kenter, S Ferrone… - Cancer Immunology …, 2008 - Springer
HLA class I loss is a significant mechanism of immune evasion by cervical carcinoma,
interfering with the development of immunotherapies and cancer vaccines. We report the …

The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G

V Cirulli, J Zalatan, M McMaster, R Prinsen… - Diabetes, 2006 - Am Diabetes Assoc
Selective expression of the human class Ib HLA molecule HLA-G in immunologically
protected sites and its function in the inhibition of NK and T-cell effector functions support an …

Polymorphism in clinical immunology–from HLA typing to immunogenetic profiling

P Jin, E Wang - Journal of translational medicine, 2003 - Springer
The pathology of humans, in contrast to that of inbred laboratory animals faces the challenge
of diversity addressed in genetic terms as polymorphism. Thus, unsurprisingly, treatment …

Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity

K Herzer, CS Falk, J Encke, ST Eichhorst… - Journal of …, 2003 - Am Soc Microbiol
The mechanisms of immune evasion and the role of the early immune response in chronic
infection caused by hepatitis C virus (HCV) are still unclear. Here, we present evidence for a …

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

K Natarajan, AC McShan, J Jiang, VK Kumirov… - Nature …, 2017 - nature.com
The molecular mechanism through which the interaction of a clonotypic αβ T-cell receptor
(TCR) with a peptide-loaded major histocompatibility complex (p/MHC) leads to T-cell …

Identifying neoantigens for use in immunotherapy

S Hutchison, AL Pritchard - Mammalian Genome, 2018 - Springer
This review focuses on the types of cancer antigens that can be recognised by the immune
system and form due to alterations in the cancer genome, including cancer testis …

CdS quantum dots/Ru (bpy) 3 2+ electrochemiluminescence resonance energy transfer system for sensitive cytosensing

MS Wu, HW Shi, JJ Xu, HY Chen - Chemical Communications, 2011 - pubs.rsc.org
In this paper, an electrochemiluminescence resonance energy transfer (ECL-RET) system
from CdS quantum dot to Ru (bpy) 32+ was developed for the first time. By the signal …