[HTML][HTML] Insoluble drug delivery strategies: review of recent advances and business prospects
S Kalepu, V Nekkanti - Acta Pharmaceutica Sinica B, 2015 - Elsevier
The emerging trends in the combinatorial chemistry and drug design have led to the
development of drug candidates with greater lipophilicity, high molecular weight and poor …
development of drug candidates with greater lipophilicity, high molecular weight and poor …
[HTML][HTML] Liposomes for enhanced bioavailability of water-insoluble drugs: In vivo evidence and recent approaches
MK Lee - Pharmaceutics, 2020 - mdpi.com
It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …
Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge
G Arzani, A Haeri, M Daeihamed… - International journal …, 2015 - Taylor & Francis
Carvedilol (CRV) is an antihypertensive drug with both alpha and beta receptor blocking
activity used to preclude angina and cardiac arrhythmias. To overcome the low, variable oral …
activity used to preclude angina and cardiac arrhythmias. To overcome the low, variable oral …
Potential of liposomes for enhancement of oral drug absorption
Oral administration of medication is the first option when patient compliance is considered.
However, many barriers face oral absorption of drugs that limit bioavailability in about 90 …
However, many barriers face oral absorption of drugs that limit bioavailability in about 90 …
[PDF][PDF] Liposomal drug delivery: a versatile platform for challenging clinical applications
Liposomes are lipid based vesicular systems that offer novel platform for versatile drug
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …
Niosome as an effective nanoscale solution for the treatment of microbial infections
Numerous disorders go untreated owing to a lack of a suitable drug delivery technology or
an appropriate therapeutic moiety, particularly when toxicities and side effects are a major …
an appropriate therapeutic moiety, particularly when toxicities and side effects are a major …
Sertaconazole nitrate loaded nanovesicular systems for targeting skin fungal infection: in-vitro, ex-vivo and in-vivo evaluation
The aim of this study was to develop different vesicular systems for sertaconazole nitrate and
evaluate the ability of targeting deep skin layers to treat dermal fungal infection. Therefore …
evaluate the ability of targeting deep skin layers to treat dermal fungal infection. Therefore …
Transforming lipid-based oral drug delivery systems into solid dosage forms: an overview of solid carriers, physicochemical properties, and biopharmaceutical …
A Tan, S Rao, CA Prestidge - Pharmaceutical research, 2013 - Springer
The diversity of lipid excipients available commercially has enabled versatile formulation
design of lipid-based drug delivery systems for enhancing the oral absorption of poorly …
design of lipid-based drug delivery systems for enhancing the oral absorption of poorly …
Proniosomes derived niosomes: recent advancements in drug delivery and targeting
Vesicular drug delivery systems have gained wide attention in the field of nanotechnology.
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …
Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties …
The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …