Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …

Page 1 Edited by Enzo Alessio WILEY-VCH Bioinorganic Medicinal Chemistry C Au Pt Ru Ga
Re B Gd Ag Tc Page 2 List of Contributors Contents Chapter 1 : Medicinal Inorganic Chemistry …

This review focuses on the current status and perspectives of the application of polyhedral
boron hydrides in medicine. The main topics discussed are boron neutron capture therapy …

The role of carboranes in medicinal chemistry has diversified in recent years and now
extends into areas of drug discovery, molecular imaging, and targeted radionuclide therapy …

The use of polyhedral boron hydrides for cancer treatment is traditionally connected with
boron neutron capture therapy. More recently, polyhedral borate anions were proposed as …

This article reviews Re and Tc organometallic chemistry and radiochemistry, focusing on the
most relevant aspects to design radiotools for molecular imaging and therapy. The review …

Radiolabeling of biologically active molecules with the [99mTc (CO) 3]+ unit has been of
primary interest in recent years. With this in mind, we herein report symmetric (L 1) and …

The synthesis of 1, 2-dicarba-closo-dodecaboranes (ortho-carboranes) is often low yielding
which is a critical issue given the increasing use of boron clusters in material science and …

Metallacarboranes have been identified as promising pharmacophores and building blocks
in drug designed as well as inhibitors of HIV. The aim of this study was to evaluate the …