Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

Redox reactions control fundamental processes of human biology. Therefore, it is safe to
assume that the responses and adaptations to exercise are, at least in part, mediated by …

Obstructive sleep apnea (OSA) is now recognized as an independent and important risk
factor for cardiovascular diseases such as hypertension, coronary heart disease, heart …

Genotoxicity refers to the ability of harmful substances to damage genetic information in
cells. Being exposed to chemical and biological agents can result in genomic instabilities …

Physical exercise represents one of the strongest physiological stimuli capable to induce
functional and structural modifications in all biological systems. Indeed, beside the …

All organisms and cells respond to various stress conditions such as environmental,
metabolic, or pathophysiological stress by generally upregulating, among others, the …

Regular physical activity is effective as prevention and treatment for different chronic
conditions related to the ageing processes. In fact, a sedentary lifestyle has been linked to a …

Regular physical activity can enhance immune function and effectively prevents the spread
of the cytokine response, thus reducing systemic low‐grade inflammation and improving …

Breast cancer (BC) is the most commonly diagnosed cancer among women worldwide and
the most common cause of cancer-related death. To date, it is still a challenge to estimate …

HSPB5 or alpha B-crystallin (CRYAB), originally identified as lens protein, is one of the most
widespread and represented of the human small heat shock proteins (sHSPs). It is greatly …