Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update
M Mmatli, NM Mbelle, J Osei Sekyere - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …
AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence
M Feldgarden, V Brover, N Gonzalez-Escalona… - Scientific reports, 2021 - nature.com
Antimicrobial resistance (AMR) is a significant public health threat. With the rise of affordable
whole genome sequencing, in silico approaches to assessing AMR gene content can be …
whole genome sequencing, in silico approaches to assessing AMR gene content can be …
Emerging Transcriptional and Genomic Mechanisms Mediating Carbapenem and Polymyxin Resistance in Enterobacteriaceae: a Systematic Review of Current …
The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …
[HTML][HTML] Silent spread of mobile colistin resistance gene mcr-9.1 on IncHI2 'superplasmids' in clinical carbapenem-resistant Enterobacterales
Abstract Objectives mcr-9.1 is a newly described mobile colistin resistance gene. We have
noted its presence in multiple species of carbapenem-resistant Enterobacterales (CRE) from …
noted its presence in multiple species of carbapenem-resistant Enterobacterales (CRE) from …
Prevalence and traits of mobile colistin resistance gene harbouring isolates from different ecosystems in Africa
The mobile colistin resistance (mcr) gene threatens the efficacy of colistin (COL), a last‐line
antibiotic used in treating deadly infections. For more than six decades, COL is used in …
antibiotic used in treating deadly infections. For more than six decades, COL is used in …
Genomic characterization of multidrug-resistant Salmonella serovar Kentucky ST198 isolated in poultry flocks in Spain (2011–2017)
C Samper-Cativiela, B Diéguez-Roda… - Microbial …, 2022 - microbiologyresearch.org
Salmonella Kentucky is commonly found in poultry and rarely associated with human
disease. However, a multidrug-resistant (MDR) S. Kentucky clone [sequence type (ST) 198] …
disease. However, a multidrug-resistant (MDR) S. Kentucky clone [sequence type (ST) 198] …
Emergence of IncHI2 Plasmids With Mobilized Colistin Resistance (mcr)-9 Gene in ESBL-Producing, Multidrug-Resistant Salmonella Typhimurium and Its …
EL Diaconu, P Alba, F Feltrin, P Di Matteo… - Frontiers in …, 2021 - frontiersin.org
A collection of 177 genomes of Salmonella Typhimurium and its monophasic variant
isolated in 2014–2019 from Italian poultry/livestock (n= 165) and foodstuff (n= 12) …
isolated in 2014–2019 from Italian poultry/livestock (n= 165) and foodstuff (n= 12) …
Characterisation of mobile colistin resistance genes (mcr-3 and mcr-5) in river and storm water in regions of the Western Cape of South Africa
Y Snyman, AC Whitelaw, JM Barnes… - … Resistance & Infection …, 2021 - Springer
Background Colistin is regarded as a last-resort antimicrobial against multi-drug resistant
Gram-negative bacteria (GNB), therefore the dissemination of colistin resistance in the …
Gram-negative bacteria (GNB), therefore the dissemination of colistin resistance in the …
[HTML][HTML] Characterisation of mcr-4.3 in a colistin-resistant Acinetobacter nosocomialis clinical isolate from Cape Town, South Africa
Y Snyman, S Reuter, AC Whitelaw, L Stein… - Journal of Global …, 2021 - Elsevier
ABSTRACT Objectives Colistin resistance in Acinetobacter spp. is increasing, resulting in
potentially untreatable nosocomial infections. Plasmid-mediated colistin resistance is of …
potentially untreatable nosocomial infections. Plasmid-mediated colistin resistance is of …
Emergence of OXA-48-producing Enterobacter hormaechei in a Swiss companion animal clinic and their genetic relationship to clinical human isolates
Background Enterobacter hormaechei producing the carbapenemase OXA-48 was
identified repeatedly in infections in companion animals hospitalized at a Swiss veterinary …
identified repeatedly in infections in companion animals hospitalized at a Swiss veterinary …