Targeting GSTP1-dependent ferroptosis in lung cancer radiotherapy: Existing evidence and future directions

X Tan, X Huang, B Niu, X Guo, X Lei… - Frontiers in Molecular …, 2022 - frontiersin.org
Radiotherapy is applied in about 70% patients with tumors, yet radioresistance of tumor cells
remains a challenge that limits the efficacy of radiotherapy. Ferroptosis, an iron-dependent …

Empowering radiotherapy: Harnessing nanomedicines to enhance radiation response and boost antitumor efficacy

X Zhuo, R Aishajiang, Y Liang, P Du, P Lei, D Yu… - Coordination Chemistry …, 2024 - Elsevier
Radiotherapy (RT) is a conventional form of tumor treatment that uses X-ray irradiation to
eliminate tumors. Although RT plays an important role in treating tumor patients and …

TRAIL-driven targeting and reversing cervical cancer radioresistance by seleno-nanotherapeutics through regulating cell metabolism

W Jiang, G Huang, S Pan, X Chen, T Liu, Z Yang… - Drug Resistance …, 2024 - Elsevier
Recently, radioresistance has become a major obstacle in the radiotherapy of cervical
cancer. To demonstrate enhanced radiosensitization against radioresistant cervical cancer …

Ovarian cancer radiosensitivity: what have we understood so far?

A Barcellini, A Charalampopoulou, L De Cecco… - Life, 2022 - mdpi.com
Radiotherapy has been increasingly considered as an active treatment to combine with
other approaches (ie, surgery, chemotherapy, and novel target-based drugs) in ovarian …

Monte Carlo simulations of microdosimetry and radiolytic species production at long time post proton irradiation using GATE and Geant4‐DNA

GR Fois, HN Tran, V Fiegel, G Blain… - Medical …, 2024 - Wiley Online Library
Background Radiobiological effectiveness of radiation in cancer treatment can be studied at
different scales (molecular till organ scale) and different time post irradiation. The production …

Charged Particle Radiotherapy for Thyroid Cancer. A systematic review

LP Ciccone, J Franzetti, M Bonora, S Ronchi… - Critical Reviews in …, 2024 - Elsevier
The role of external beam radiotherapy (EBRT) in thyroid cancer (TC) remains contentious
due to limited data. Retrospective studies suggest adjuvant EBRT benefits high-risk …

[HTML][HTML] Antioxidants Hydroxytyrosol and Thioredoxin-Mimetic Peptide CB3 Protect Irradiated Normal Tissue Cells

K Borrmann, FM Troschel, KA Brücksken… - Antioxidants, 2024 - mdpi.com
Reducing side effects in non-cancerous tissue is a key aim of modern radiotherapy. Here,
we assessed whether the use of the antioxidants hydroxytyrosol (HT) and thioredoxin …

Insights into antioxidant strategies to counteract radiation-induced male infertility

MA Spadella, EJR Silva, AB Chies… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Radiotherapy, which employs ionizing radiation to destroy or prevent the
multiplication of tumor cells, has been increasingly used in the treatment of neoplastic …

Radiation Therapy for Gestational Trophoblastic Neoplasia: Forward-Looking Lessons Learnt

A Barcellini, A Fodor, A Charalampopoulou, C Cassani… - Cancers, 2023 - mdpi.com
Simple Summary The management of high-risk gestational trophoblastic neoplasia is
multimodal, requiring a multimodality treatment that might include radiotherapy, especially in …

Radiation-activated nanoparticles: Which combination to optimize radiosensitization?

S Penninckx, P Martinive, C Mirjolet - Cancer/Radiothérapie, 2023 - Elsevier
Radiotherapy plays a crucial role in the treatment of various cancers. With the ongoing
technological advancements in radiotherapy equipment, allowing for increasingly precise …