How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

Active systems, from bacterial suspensions to cellular monolayers, are continuously driven
out of equilibrium by local injection of energy from their constituent elements and exhibit …

During vertebrate embryogenesis, cell collectives engage in coordinated behavior to form
tissue structures of increasing complexity. In the avian skin, assembly into follicles depends …

Morphological trends in growing colonies of living cells are at the core of physiological and
evolutionary processes. Using active gel equations, which include cell division, we show …

Cell-free studies have demonstrated how collective action of actin-associated proteins can
organize actin filaments into dynamic patterns, such as vortices, asters and stars. Using …

The actomyosin cytoskeleton is responsible for most force-driven processes in cells and
tissues. How it assembles into the necessary structures at the right time and place is an …

Mechanochemical processes in thin biological structures, such as the cellular cortex or
epithelial sheets, play a key role during the morphogenesis of cells and tissues. In particular …