MERTK in cancer therapy: Targeting the receptor tyrosine kinase in tumor cells and the immune system
JM Huelse, DM Fridlyand, S Earp, D DeRyckere… - Pharmacology & …, 2020 - Elsevier
The receptor tyrosine kinase MERTK is aberrantly expressed in numerous human
malignancies, and is a novel target in cancer therapeutics. Physiologic roles of MERTK …
malignancies, and is a novel target in cancer therapeutics. Physiologic roles of MERTK …
MERTK mutation update in inherited retinal diseases
I Audo, S Mohand‐Said… - Human …, 2018 - Wiley Online Library
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane
of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment …
of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment …
Mertk inhibition: potential as a treatment strategy in egfr tyrosine kinase inhibitor-resistant non-small cell lung cancer
CJ Chen, YP Liu - Pharmaceuticals, 2021 - mdpi.com
Epidermal growth factor tyrosine kinase inhibitors (EGFR-TKIs) are currently the most
effective treatment for non-small cell lung cancer (NSCLC) patients, who carry primary EGFR …
effective treatment for non-small cell lung cancer (NSCLC) patients, who carry primary EGFR …
Identification of novel USH2A mutations in patients with autosomal recessive retinitis pigmentosa via targeted next‑generation sequencing
X Zhu, X Li, W Tian, Y Yang… - Molecular Medicine …, 2020 - spandidos-publications.com
Retinitis pigmentosa (RP) is a group of inheritable blindness retinal diseases characterized
by the death of photoreceptor cells and a gradual loss of peripheral vision. Mutations in …
by the death of photoreceptor cells and a gradual loss of peripheral vision. Mutations in …
Unravelling the genetic basis of retinal dystrophies in Pakistani consanguineous families
Abstract Background Retinitis Pigmentosa (RP) is a clinically and genetically progressive
retinal dystrophy associated with severe visual impairments and sometimes blindness, the …
retinal dystrophy associated with severe visual impairments and sometimes blindness, the …