The oncogenic fusion landscape in pediatric CNS neoplasms
Pediatric neoplasms in the central nervous system (CNS) are the leading cause of cancer-
related deaths in children. Recent developments in molecular analyses have greatly …
related deaths in children. Recent developments in molecular analyses have greatly …
Invited review: DNA methylation‐based classification of paediatric brain tumours
E Perez, D Capper - Neuropathology and applied …, 2020 - Wiley Online Library
DNA methylation‐based machine learning algorithms represent powerful diagnostic tools
that are currently emerging for several fields of tumour classification. For various reasons …
that are currently emerging for several fields of tumour classification. For various reasons …
High‐grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication—a comprehensive clinical, radiographic, pathologic, and genomic analysis
SP Ferris, J Velazquez Vega, M Aboian, JC Lee… - Brain …, 2020 - Wiley Online Library
High‐grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication (HGNET
BCOR ex15 ITD) is a recently proposed tumor entity of the central nervous system (CNS) …
BCOR ex15 ITD) is a recently proposed tumor entity of the central nervous system (CNS) …
Genomic profiling of BCOR-rearranged uterine sarcomas reveals novel gene fusion partners, frequent CDK4 amplification and CDKN2A loss
DI Lin, A Hemmerich, C Edgerly, D Duncan… - Gynecologic …, 2020 - Elsevier
Objective Genomic alterations of BCOR via ZC3H7B-BCOR fusion or BCOR internal tandem
duplication (ITD) define a subset of endometrial stromal sarcoma (ESS). The goals of this …
duplication (ITD) define a subset of endometrial stromal sarcoma (ESS). The goals of this …
Expanding the clinicopathologic and molecular spectrum of BCOR‐associated sarcomas in adults
A Yoshida, Y Arai, N Hama, H Chikuta, Y Bando… - …, 2020 - Wiley Online Library
Aims BCOR gene alteration is a genetic signature of rare subsets of sarcomas. Most BCOR‐
associated sarcomas thus far reported are in the pediatric population, except for uterine …
associated sarcomas thus far reported are in the pediatric population, except for uterine …
Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children's Research Hospital including the multi-center …
Methylation profiling has radically transformed our understanding of tumors previously
called central nervous system primitive neuro-ectodermal tumors (CNS-PNET). While this …
called central nervous system primitive neuro-ectodermal tumors (CNS-PNET). While this …
Molecular pathogenesis and prognostication of" low‐grade''and" high‐grade" endometrial stromal sarcoma
F Micci, S Heim, I Panagopoulos - Genes, Chromosomes and …, 2021 - Wiley Online Library
Endometrial stromal sarcomas (ESS) are a heterogeneous group of rare mesenchymal
cancers. Considerable knowledge has been gained in recent years about the molecular …
cancers. Considerable knowledge has been gained in recent years about the molecular …
[HTML][HTML] Rare embryonal and sarcomatous central nervous system tumours: State-of-the art and future directions
J Gojo, M Kjaersgaard, B Zezschwitz, D Capper… - European Journal of …, 2023 - Elsevier
The introduction of molecular methods into the diagnostics of central nervous system (CNS)
tumours and the subsequent deciphering of their molecular heterogeneity has resulted in a …
tumours and the subsequent deciphering of their molecular heterogeneity has resulted in a …
Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions
The BCL6 corepressor gene (BCOR) is a tumor suppressor gene located on human
chromosome X that regulates cell differentiation and body structure development [2] …
chromosome X that regulates cell differentiation and body structure development [2] …
CNS tumor with CREBBP::BCORL1 Fusion and pathogenic mutations in BCOR and CREBBP: expanding the spectrum of BCOR-altered tumors
The fifth edition of the World Health Organization (WHO) classification of central nervous
system (CNS) tumors introduced the new tumor type CNS tumor with BCOR internal tandem …
system (CNS) tumors introduced the new tumor type CNS tumor with BCOR internal tandem …