Background: Smoking-associated DNA methylation levels identified through epigenome-
wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms …

Spontaneous dizygotic (DZ) twins, ie twins conceived without the use of ARTs, run in
families and their prevalence varies widely around the globe. In contrast, monozygotic (MZ) …

Epigenetic dysregulation is implicated in the pathogenesis of lupus. We performed a
longitudinal analysis to assess changes in DNA methylation in lupus neutrophils over 4 …

The evolving field of multi‐omics combines data and provides methods for simultaneous
analysis across several omics levels. Here, we integrated genomics (transmitted and non …

We examined the performance of methylation scores (MS) and polygenic scores (PGS) for
birth weight, BMI, prenatal maternal smoking exposure, and smoking status to assess the …

Background Applying good data management and FAIR (Findable, Accessible,
Interoperable, and Reusable) data principles in research projects can help disentangle …

This study introduces and illustrates the potential of an integrated multi-omics approach in
investigating the underlying biology of complex traits such as childhood aggressive …

Breastfeeding has long-term benefits for children that may be mediated via the epigenome.
This pathway has been hypothesized, but the number of empirical studies in humans is …

Objectives Lupus T cells demonstrate aberrant DNA methylation patterns dominated by
hypomethylation of interferon-regulated genes. The objective of this study was to identify …

The human umbilical cord (hUC) is the lifeline that connects the fetus to the mother.
Hypercoiling of the hUC is associated with pre-and perinatal morbidity and mortality. We …