Cytokines, hormones and cellular regulatory mechanisms favoring successful reproduction

MP Piccinni, R Raghupathy, S Saito… - Frontiers in …, 2021 - frontiersin.org
Its semi-allogeneic nature renders the conceptus vulnerable to attack by the maternal
immune system. Several protective mechanisms operate during gestation to correct the …

Progesterone as an anti-inflammatory drug and immunomodulator: new aspects in hormonal regulation of the inflammation

TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Biomolecules, 2022 - mdpi.com
The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …

Progesterone: a unique hormone with immunomodulatory roles in pregnancy

R Raghupathy, J Szekeres-Bartho - International journal of molecular …, 2022 - mdpi.com
Progesterone is well known for its numerous endocrinologic roles in pregnancy but is also
endowed with fascinating immunomodulatory capabilities. It can downregulate the induction …

[HTML][HTML] Inhalation and ingestion of Synthetic musks in pregnant women: In silico spontaneous abortion risk evaluation and control

X Li, Y Zhao, B Chen, Z Zhu, Q Kang, T Husain… - Environment …, 2022 - Elsevier
Synthetic musks (SMs) are odor additives commonly used in the personal care products.
Their wide existence in the environment and the recently reported adverse impact on the …

Natural killer cells in recurrent miscarriage: An overview

B Guerrero, F Hassouneh, E Delgado… - Journal of Reproductive …, 2020 - Elsevier
Recurrent Miscarriage is an early pregnancy complication which affects about 1–3% of child-
bearing couples. The mechanisms involved in the occurrence of recurrent miscarriages are …

Impact of estrogen and progesterone on immune cells and host–pathogen interactions in the lower female reproductive tract

MK Collins, CR McCutcheon… - The Journal of …, 2022 - journals.aai.org
Microbial infections are a threat to women's reproductive health. Although reproductive
cycles and pregnancy are controlled by sex hormones, the impact of hormones on host …

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

JG Lee, JM Yon, G Kim, SG Lee, CY Kim… - Nature …, 2024 - nature.com
Proper placental development in early pregnancy ensures a positive outcome later on. The
developmental relationship between the placenta and embryonic organs, such as the heart …

Mechanism analysis of synthetic musks-induced miscarriage risk in pregnant women: Molecular and adverse outcome pathways perspectives

X Li, R Li, M Du, Q Li, D Liu - Science of The Total Environment, 2023 - Elsevier
Synthetic musks (SMs) with pleasant odor have been extensively used in personal care
products. SMs are emerging contaminants due to the wide detection in human breast milk …

Luteal phase in assisted reproductive technology

J Tesarik, C Conde-López, M Galán-Lázaro… - … in Reproductive Health, 2020 - frontiersin.org
Luteal phase (LP) is the period of time beginning shortly after ovulation and ending either
with luteolysis, shortly before menstrual bleeding, or with the establishment of pregnancy …

Metabolomic profiling of biological reference materials using a multiplatform high-resolution mass spectrometric approach

JJ Aristizabal-Henao, DJ Lemas, EK Griffin… - Journal of the …, 2021 - ACS Publications
The number of metabolomics studies have increased dramatically in recent years, spanning
from basic/mechanistic research to the identification and validation of clinical biomarkers …