[HTML][HTML] The clinical implications of bacterial pathogenesis and mucosal immunity in chronic urinary tract infection

CCY Chieng, Q Kong, NSY Liou, R Khasriya… - Mucosal …, 2023 - Elsevier
Urinary tract infections (UTIs) exert a significant health and economic cost globally.
Approximately one in four people with a previous history of UTI continue to develop …

Emerging non-antibiotic options targeting uropathogenic mechanisms for recurrent uncomplicated urinary tract infection

YC Chen, WC Lee, YC Chuang - International journal of molecular …, 2023 - mdpi.com
Urinary tract infections (UTIs) are the most frequent bacterial infections in the clinical setting.
Even without underlying anatomic or functional abnormalities, more than 40% of women …

Urinary Tract Infections Caused by Uropathogenic Escherichia coli Strains—New Strategies for an Old Pathogen

C Zagaglia, MG Ammendolia, L Maurizi, M Nicoletti… - Microorganisms, 2022 - mdpi.com
Urinary tract infections (UTIs) are among the most common infections worldwide.
Uropathogenic Escherichia coli (UPECs) are the main causative agent of UTIs. UPECs …

Urinary tract infection and microbiome

DS Kim, JW Lee - Diagnostics, 2023 - mdpi.com
Urinary tract infection is one of the most common bacterial infections and can cause major
burdens, not only to individuals but also to an entire society. Current knowledge of the …

Advanced organotypic in vitro model systems for host–microbial coculture

R Kim - Biochip journal, 2023 - Springer
In vitro model systems have been advanced to recapitulate important physiological features
of the target organ in vivo more closely than the conventional cell line cultures on a petri …

Survey of the infant male urobiome and genomic analysis of Actinotignum spp.

SA Reasoner, V Flores, G Van Horn… - npj Biofilms and …, 2023 - nature.com
The urinary bladder harbors a community of microbes termed the urobiome, which remains
understudied. In this study, we present the urobiome of healthy infant males from samples …

Correlation between antimicrobial resistance, biofilm formation, and virulence determinants in uropathogenic Escherichia coli from Egyptian hospital

SA Alshaikh, T El-Banna, F Sonbol… - Annals of Clinical …, 2024 - Springer
Abstract Background Uropathogenic Escherichia coli (UPEC) is the main etiological agent
behind community-acquired and hospital-acquired urinary tract infections (UTIs), which are …

The role of NLRP3 in regulation of antimicrobial peptides and estrogen signaling in UPEC-infected bladder epithelial cells

A Lindblad, R Wu, K Persson, I Demirel - Cells, 2023 - mdpi.com
The NLRP3 inflammasome, estrogen and antimicrobial peptides have all been found to
have a vital role in the protection of the bladder urothelium. However, the interdependence …

Uropathogenic Escherichia coli endeavors: an insight into the characteristic features, resistance mechanism, and treatment choice

V Arafi, A Hasani, J Sadeghi, M Varshochi… - Archives of …, 2023 - Springer
Uropathogenic Escherichia coli (UPEC) are the strains diverted from the intestinal status and
account mainly for uropathogenicity. This pathotype has gained specifications in structure …

Biomarkers for urinary tract infection: present and future perspectives

TK Mattoo, JD Spencer - Pediatric Nephrology, 2024 - Springer
A prompt diagnosis of urinary tract infection (UTI) is necessary to minimize its symptoms and
limit sequelae. The current UTI screening by urine test strip analysis and microscopic …