Two-component regulatory systems (TCRSs) mediate cellular response by coupling sensing and regulatory mechanisms. TCRSs are comprised of a histidine kinase (HK), which serves …
Implanted biomaterials are coated immediately with host plasma constituents, including extracellular matrix (ECM); this reaction may be undesirable in some cases. Poly (l-lysine) …
Bacterial cell-surface display systems coupled with quantitative screening methods offer the potential to expand protein engineering capabilities. To more fully exploit this potential, a …
RR Maddikeri, S Tosatti, M Schuler… - … Research Part A, 2008 - Wiley Online Library
Ideally, implants should inhibit nonspecific protein adsorption, bacterial adhesion, and at the same time, depending on the final application be selective toward cellular adhesion and …
S Ravikumar, I Ganesh, I Yoo, SH Hong - Process Biochemistry, 2012 - Elsevier
In this study, we designed and applied molecular biosensors for heavy metals, zinc and copper, for use in bioremediation strategies. Bacteria utilize two component systems to …
H Wernérus, S Ståhl - Biotechnology and applied biochemistry, 2004 - Wiley Online Library
Display of heterologous proteins on the surface of micro‐organisms, enabled by means of recombinant DNA technology, has become an increasingly popular strategy in microbiology …
JJ Rice, A Schohn, PH Bessette, KT Boulware… - Protein …, 2006 - Wiley Online Library
A bacterial display methodology was developed for N‐and C‐terminal display and demonstrated to enable rapid screening of very large peptide libraries with high precision …
A Schubert, K Zakikhany, G Pietrocola… - Infection and …, 2004 - Am Soc Microbiol
Streptococcus agalactiae is a major cause of bacterial pneumonia, sepsis, and meningitis in human neonates. During the course of infection, S. agalactiae adheres to a variety of …
NA Khan, N Barthes, G McCormack… - Journal of Applied …, 2023 - academic.oup.com
Aim A promising approach for the development of next-generation antimicrobials is to shift their target from causing bacterial death to inhibiting virulence. Marine sponges are an …