Parkinson's disease: a review from pathophysiology to treatment
BLB Marino, LR de Souza, KPA Sousa… - Mini reviews in …, 2020 - benthamdirect.com
Parkinson's Disease (PD) is the second most common neurodegenerative disease in the
elderly population, with a higher prevalence in men, independent of race and social class; it …
elderly population, with a higher prevalence in men, independent of race and social class; it …
[HTML][HTML] Gastrointestinal and hepatic diseases during the COVID-19 pandemic: Manifestations, mechanism and management
DZ Mohamed, MES Ghoneim… - World journal of …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered the
causative pathogen of coronavirus disease 2019 (COVID-19) and has become an …
causative pathogen of coronavirus disease 2019 (COVID-19) and has become an …
Trihexyphenidyl Alters Its Host's Metabolism, Neurobehavioral Patterns, and Gut Microbiome Feedback Loop—The Modulating Role of Anacyclus pyrethrum
A Baslam, H Azraida, R Aboufatima, M Ait-El-Mokhtar… - Antioxidants, 2023 - mdpi.com
Trihexyphenidyl (THP)—a synthetic anticholinergic medication used to manage
parkinsonism and extrapyramidal symptoms—has gained significant clinical recognition …
parkinsonism and extrapyramidal symptoms—has gained significant clinical recognition …
Dystonia
Dystonia is a common movement disorder involving abnormal, often twisting postures and is
a challenging condition to diagnose as we present here in a comprehensive overview. The …
a challenging condition to diagnose as we present here in a comprehensive overview. The …
The dystonia coalition: a multicenter network for clinical and translational studies
G Kilic-Berkmen, LJ Wright, JS Perlmutter… - Frontiers in …, 2021 - frontiersin.org
Dystonia is a movement disorder characterized by sustained or intermittent muscle
contractions causing abnormal postures, repetitive movements, or both. Research in …
contractions causing abnormal postures, repetitive movements, or both. Research in …
A novel reduced graphene oxide modified carbon paste electrode for potentiometric determination of trihexyphenidyl hydrochloride in pharmaceutical and biological …
A novel promising carbon paste electrode with excellent potentiometric properties was
prepared for the analysis of trihexyphenidyl hydrochloride (THP), the acetylcholine receptor …
prepared for the analysis of trihexyphenidyl hydrochloride (THP), the acetylcholine receptor …
SPARSE: a sparse hypergraph neural network for learning multiple types of latent combinations to accurately predict drug–drug interactions
Motivation Predicting side effects of drug–drug interactions (DDIs) is an important task in
pharmacology. The state-of-the-art methods for DDI prediction use hypergraph neural …
pharmacology. The state-of-the-art methods for DDI prediction use hypergraph neural …
The neurobiological basis for novel experimental therapeutics in dystonia
Dystonia is a movement disorder characterized by involuntary muscle contractions, twisting
movements, and abnormal postures that may affect one or multiple body regions. Dystonia is …
movements, and abnormal postures that may affect one or multiple body regions. Dystonia is …
Discovery of the First Selective M4 Muscarinic Acetylcholine Receptor Antagonists with in Vivo Antiparkinsonian and Antidystonic Efficacy
Nonselective antagonists of muscarinic acetylcholine receptors (mAChRs) that broadly
inhibit all five mAChR subtypes provide an efficacious treatment for some movement …
inhibit all five mAChR subtypes provide an efficacious treatment for some movement …
Dopamine-receptor blocking agent-associated akathisia: a summary of current understanding and proposal for a rational approach to treatment
S Musco, V McAllister, I Caudle - Therapeutic Advances in …, 2020 - journals.sagepub.com
Dopamine-receptor blocking agent-associated akathisia (DRBA-A) is an adverse effect that
can significantly limit the use of these important medications for the treatment of a variety of …
can significantly limit the use of these important medications for the treatment of a variety of …