Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Quasi-LD-Targeted and ONOO-Responsive Fluorescent Probe for Investigating the Interaction of Nonalcoholic Fatty Liver with Drug-Induced Liver Injury

N Wang, X Lu, J Wang, H Wang, B Zhang… - Analytical …, 2023 - ACS Publications
Hepatic lipid droplets (LDs) and peroxynitrite (ONOO–) levels are closely related to
nonalcoholic fatty liver disease (NAFLD). Additionally, some drug-induced liver injury (DILI) …

Lipid Droplet-Specific Fluorescent Probe for In Vivo Visualization of Polarity in Fatty Liver, Inflammation, and Cancer Models

L Fan, X Wang, Q Zan, L Fan, F Li, Y Yang… - Analytical …, 2021 - ACS Publications
Elucidating the intrinsic relationship between diseases and lipid droplet (LD) polarity
remains a great challenge owing to the lack of the research on multiple disease models …

Recent advances and perspectives in reaction-based fluorescent probes for imaging peroxynitrite in biological systems

WL Cui, MH Wang, YH Yang, JY Wang, X Zhu… - Coordination Chemistry …, 2023 - Elsevier
Peroxynitrite, one of the most active reactive oxygen (ROS) and reactive nitrogen (RON)
species, has been of wide interest because of its high oxidizing and nitrifying properties. As …

Lipid droplet targeting type I photosensitizer for ferroptosis via lipid peroxidation accumulation

T Xiong, Y Chen, Q Peng, S Lu, S Long, M Li… - Advanced …, 2024 - Wiley Online Library
As an iron‐dependent lipid peroxidation (LPO) mediated cell death pathway, ferroptosis
offers promises for anti‐tumor treatment. Photodynamic therapy (PDT) is an ideal way to …

Exploiting the twisted intramolecular charge transfer effect to construct a wash-free solvatochromic fluorescent lipid droplet probe for fatty liver disease diagnosis

CJ Wu, XY Li, T Zhu, M Zhao, Z Song, S Li… - Analytical …, 2022 - ACS Publications
The prominent pathological feature of fatty liver disease lesions is excessive fat
accumulation in lipid droplets in hepatocytes. Thus, developing fluorescent lipid droplet …

A near-infrared probe for specific imaging of lipid droplets in living cells

X Wu, X Wang, Y Li, F Kong, K Xu, L Li… - Analytical …, 2022 - ACS Publications
Lipid droplets (LDs) are involved in various physiological processes and associated with
cancer development, and are regarded as a potential tumor marker for cancer diagnosis …

Engineering of a NIR fluorescent probe for high-fidelity tracking of lipid droplets in living cells and nonalcoholic fatty liver tissues

J Hong, Y Liu, X Tan, G Feng - Biosensors and Bioelectronics, 2023 - Elsevier
LDs (Lipid droplets) are key organelles for lipid metabolism and storage, which are closely
related to ferroptosis and fatty liver. Due to its small size and highly dynamic nature …