Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Endothelial cells, which form the inner cellular lining of blood vessels and lymphatics,
display remarkable heterogeneity in structure and function. This is the first of a 2-part review …

Background—Indirect evidence implicates endothelial dysfunction in the pathogenesis of
vascular diseases associated with obstructive sleep apnea (OSA). We investigated directly …

Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

Background—Unrecognized obstructive sleep apnea (OSA) is highly prevalent in obesity.
Both obesity and OSA are associated with vascular endothelial inflammation and increased …

It has become increasingly clear that the Notch signaling pathway plays a critical role in the
development and homeostasis of the cardiovascular system. This notion has emerged from …

Obstructive sleep apnea (OSA) affects 25% of the Western adult population. It is an
independent but seldom-recognized risk factor for hypertension, myocardial infarction …

Objective—Psoriasis is an inflammatory skin disease which heightens the risk of
cardiovascular disease. This study directly investigated vascular endothelial health and …

The endothelium is an expansive spatially distributed organ. 1 Endothelial cells participate
in a large number of physiological processes including the control of vasomotor tone, the …

Atherosclerotic arterial occlusive disease affecting the lower extremities is also known as
peripheral artery disease (PAD). This disorder affects 8 to 12 million individuals in the US …