Grounding neuroscience in behavioral changes using artificial neural networks

GW Lindsay - Current opinion in neurobiology, 2024 - Elsevier
Connecting neural activity to function is a common aim in neuroscience. How to define and
conceptualize function, however, can vary. Here I focus on grounding this goal in the specific …

Applications of deep learning for drug discovery systems with bigdata

Y Matsuzaka, R Yashiro - BioMedInformatics, 2022 - mdpi.com
The adoption of “artificial intelligence (AI) in drug discovery”, where AI is used in the process
of pharmaceutical research and development, is progressing. By using the ability to process …

Emergence of cortical network motifs for short-term memory during learning

XW Chia, JK Tan, LF Ang, T Kamigaki… - Nature …, 2023 - nature.com
Learning of adaptive behaviors requires the refinement of coordinated activity across
multiple brain regions. However, how neural communications develop during learning …

Representational spaces in orbitofrontal and ventromedial prefrontal cortex: task states, values, and beyond

N Moneta, S Grossman, NW Schuck - Trends in Neurosciences, 2024 - cell.com
The orbitofrontal cortex (OFC) and ventromedial-prefrontal cortex (vmPFC) play a key role in
decision-making and encode task states in addition to expected value. We review evidence …

Spiking Variational Policy Gradient for Brain Inspired Reinforcement Learning

Z Yang, S Guo, Y Fang, Z Yu… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Recent studies in reinforcement learning have explored brain-inspired function
approximators and learning algorithms to simulate brain intelligence and adapt to …

Trends innovations challenges in employing interdisciplinary approaches to biomedical sciences

MG Kumar, S Ayyadhury, E Murugan - Translational Research in …, 2024 - Springer
The last few decades have seen the stepwise incorporation of multitude of disciplines of
computer sciences, physics, chemistry, mathematics, engineering, and information …

Arithmetic value representation for hierarchical behavior composition

H Makino - Nature neuroscience, 2023 - nature.com
The ability to compose new skills from a preacquired behavior repertoire is a hallmark of
biological intelligence. Although artificial agents extract reusable skills from past experience …

Biologically plausible variational policy gradient with spiking recurrent winner-take-all networks

Z Yang, S Guo, Y Fang, JK Liu - arXiv preprint arXiv:2210.13225, 2022 - arxiv.org
One stream of reinforcement learning research is exploring biologically plausible models
and algorithms to simulate biological intelligence and fit neuromorphic hardware. Among …

What Makes a Face Look like a Hat: Decoupling Low-level and High-level Visual Properties with Image Triplets

M Piriyajitakonkij, S Itthipuripat, I Ballard… - arXiv preprint arXiv …, 2024 - arxiv.org
In visual decision making, high-level features, such as object categories, have a strong
influence on choice. However, the impact of low-level features on behavior is less …

A Model of Place Field Reorganization During Reward Maximization

MG Kumar, B Bordelon, JA Zavatone-Veth… - bioRxiv, 2024 - biorxiv.org
When rodents learn to navigate in a novel environment, a high density of place fields
emerges at reward locations, fields elongate against the trajectory, and individual fields …