P Gautret, R Steffen - International Journal of Infectious Diseases, 2016 - Elsevier
Mass gatherings are characterized by the concentration of people temporally and spatially, and may lead to the emergence of infectious diseases due to enhanced transmission …
J Kubacki, C Fraefel… - Journal of Veterinary …, 2021 - journals.sagepub.com
The value of next-generation sequencing (NGS)-based applications for testing purposes in human medicine is widely recognized. Although NGS-based metagenomic screening may …
Around 2008 or 2009, an influenza A virus that had been circulating undetected in swine entered human population. Unlike most swine influenza infections of humans, this virus …
CL Kao, TC Chan, CH Tsai, KY Chu, SF Chuang… - PLoS …, 2012 - journals.plos.org
The 2009 influenza pandemic provided an opportunity to observe dynamic changes of the hemagglutinin (HA) and neuraminidase (NA) of pH1N1 strains that spread in two …
V Zima, CB Albiñana, K Rojíková, J Pokorná… - Bioorganic & Medicinal …, 2019 - Elsevier
This study focuses on design, synthesis and in vitro evaluation of inhibitory potency of two series of sialylmimetic that target an exosite (“150-cavity”) adjacent to the active site of …
RM Neri-Bazán, J García-Machorro… - European Journal of …, 2017 - Elsevier
Since the neuraminidase (NA) enzyme of the influenza A virus plays a key role in the process of release of new viral particles from a host cell, it is often a target for new drug …
S Ear - Politics and the life sciences, 2012 - cambridge.org
Emerging infectious diseases (EIDs) pose international security threats because of their potential to inflict harm upon humans, crops, livestock, health infrastructure, and economies …
AN Brown, JJ McSharry, Q Weng… - Antimicrobial agents …, 2011 - Am Soc Microbiol
In 2009, a novel H1N1 influenza A virus emerged and spread worldwide, initiating a pandemic. Various isolates obtained from disparate parts of the world were shown to be …
R Arellano-Llamas, L Alfaro-Ruiz, C Arriaga Canon… - PloS One, 2017 - journals.plos.org
Since the emergence of the pandemic H1N1pdm09 virus in Mexico and California, biannual increases in the number of cases have been detected in Mexico. As observed in previous …