Commercially approved vaccines for canine leishmaniosis: a review of available data on their safety and efficacy

R Velez, M Gállego - Tropical Medicine & International Health, 2020 - Wiley Online Library
Canine leishmaniosis is an important vector‐borne zoonosis caused mainly by Leishmania
infantum. Diagnosis and treatment of affected individuals can be particularly complex …

The balancing act: Immunology of leishmaniosis

AJ Toepp, CA Petersen - Research in veterinary science, 2020 - Elsevier
Immune control of Leishmania infantum, the causative agent of most canine leishmaniosis
(CanL), requires a balancing act between inflammatory and regulatory responses. This …

[图书][B] Parasitology: a conceptual approach

ES Loker, BV Hofkin - 2022 - taylorfrancis.com
Produced amidst the still rippling effects of a pandemic and as the world experiences the
increasing burden of global warming and a rapidly changing biosphere, the second edition …

Comorbid infections induce progression of visceral leishmaniasis

AJ Toepp, GRG Monteiro, JFV Coutinho, AL Lima… - Parasites & vectors, 2019 - Springer
Background Visceral leishmaniasis (VL) is a vector borne zoonotic disease endemic in
humans and dogs in Brazil. Due to the increased risk of human infection secondary to the …

Randomized, controlled, double-blinded field trial to assess Leishmania vaccine effectiveness as immunotherapy for canine leishmaniosis

A Toepp, M Larson, G Wilson, T Grinnage-Pulley… - Vaccine, 2018 - Elsevier
Better tools are necessary to eliminate visceral leishmaniasis (VL). Modeling studies for
regional Leishmania elimination indicate that an effective vaccine is a critical tool. Dogs are …

Immunotherapy in clinical canine leishmaniosis: a comparative update

M Baxarias, P Martínez-Orellana, G Baneth… - Research in veterinary …, 2019 - Elsevier
Leishmaniosis due to Leishmania infantum is a complex infection that can affect both
humans and dogs, and present a wide range of clinical signs and clinicopathological …

Latest trends in L. infantum infection in dogs in Spain, Part II: current clinical management and control according to a national survey of veterinary practitioners

A Montoya, R Gálvez, R Checa, J Sarquis, A Plaza… - Parasites & vectors, 2020 - Springer
Abstract Background Canine leishmaniosis (CanL) is a parasitic zoonotic disease, endemic
in the Mediterranean basin including Spain. While knowledge about CanL, its management …

Maternal Leishmania infantum infection status has significant impact on leishmaniasis in offspring

AJ Toepp, C Bennett, B Scott, R Senesac… - PLoS neglected …, 2019 - journals.plos.org
Visceral Leishmaniasis is a deadly disease caused by Leishmania infantum, endemic in
more than 98 countries across the globe. Although the most common means of transmission …

[PDF][PDF] Activity of benzimidazole derivatives and their N-heterocyclic carbene silver complexes against leishmania major promastigotes and amastigotes

TA Khan, A Mnasri, IS Al Nasr… - … Res. Appl. Chem, 2022 - biointerfaceresearch.com
Little progress was conducted concerning discovering new efficient antileishmanial drugs for
many years. Hence, the disease has become a global health problem meanwhile …

A blinded, randomized and controlled multicenter clinical trial to assess the efficacy and safety of Leisguard® as an immunotherapeutic treatment for healthy …

M Baxarias, G Donato, C Mateu, M Salichs… - Parasites & vectors, 2023 - Springer
Abstract Background Domperidone (Leisguard®) is an immunomodulatory drug used as a
preventive measure in healthy dogs. However, no studies have been published in healthy …