Membrane-bound myosin IC drives the chiral rotation of the gliding actin filament around its longitudinal axis
Y Sato, K Yoshimura, K Matsuda, T Haraguchi… - Scientific Reports, 2023 - nature.com
Myosin IC, a single-headed member of the myosin I family, specifically interacts with anionic
phosphatidylinositol 4, 5-bisphosphate (PI [4, 5] P2) in the cell membrane via the pleckstrin …
phosphatidylinositol 4, 5-bisphosphate (PI [4, 5] P2) in the cell membrane via the pleckstrin …
[HTML][HTML] Actin-Membrane Linkers: Insights from Synthetic Reconstituted Systems
At the cell surface, the actin cytoskeleton and the plasma membrane interact reciprocally in a
variety of processes related to the remodeling of the cell surface. The actin cytoskeleton has …
variety of processes related to the remodeling of the cell surface. The actin cytoskeleton has …
Left–right Myosin‐Is, Myosin1C, and Myosin1D exhibit distinct single molecule behaviors on the plasma membrane of Drosophila macrophages
S Utsunomiya, K Takebayashi, A Yamaguchi… - Genes to …, 2024 - Wiley Online Library
Left–right (LR) asymmetry is crucial for animal development, particularly in Drosophila
where LR‐asymmetric morphogenesis of organs hinges on cellular‐level chirality, termed …
where LR‐asymmetric morphogenesis of organs hinges on cellular‐level chirality, termed …
[HTML][HTML] Myosin-I Synergizes with Arp2/3 Complex to Enhance Pushing Forces of Branched Actin Networks
Abstract Myosin-Is colocalize with Arp2/3 complex-nucleated actin networks at sites of
membrane protrusion and invagination, but the mechanisms by which myosin-I motor activity …
membrane protrusion and invagination, but the mechanisms by which myosin-I motor activity …
High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory
SS Chavali, PJ Carman, H Shuman, EM Ostap… - bioRxiv, 2025 - biorxiv.org
Myosin-IC (myo1c) uses an ATP-driven'power-stroke'to support slow intracellular membrane
and vesicle transport. We used cryo-electron microscopy to understand adaptations of …
and vesicle transport. We used cryo-electron microscopy to understand adaptations of …