[HTML][HTML] NF-κB inhibitors gifted by nature: The anticancer promise of polyphenol compounds

C Guan, X Zhou, H Li, X Ma, J Zhuang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Polyphenol compounds are natural antioxidants, which are rich in anti-inflammatory and
antioxidant components. They have a wide range of medicinal benefits that are believed to …

[HTML][HTML] Nutraceutical-based telomerase inhibitors: Renewed hope for cancer therapy

YF Mustafa - Phytomedicine Plus, 2024 - Elsevier
Background: Attributes of potential targets for anticancer therapy are currently being
investigated for telomeres, telomerase, and their combined complex. Study Design …

[HTML][HTML] Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway

X Cheng, F Wang, Y Qiao, T Chen, L Fan… - Chemico-biological …, 2023 - Elsevier
Tumor angiogenesis, which may be affected by microenvironmental inflammation and
promotes tumor development and metastasis, is one of the key reasons contributing to …

The natural compound Sanggenon C inhibits PRRSV infection by regulating the TRAF2/NF-κB signalling pathway

X Liu, Y Zhu, D Wang, R Feng, Z Chen, Z Zheng… - Veterinary …, 2023 - Springer
Porcine reproductive and respiratory syndrome (PRRS) is a serious infectious disease and
one of the major causes of death in the global pig industry. PRRS virus (PRRSV) strains …

NF-kB (p50/p65)-Mediated Pro-Inflammatory microRNA (miRNA) Signaling in Alzheimer's Disease (AD)

WJ Lukiw - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
A small family of NF-kB (p50/p65)-regulated microRNAs (miRNAs) has been identified and
partially characterized in Alzheimer's disease (AD) brain in the hippocampal CA1 and …

Design of Sonosensitizers Integrated with Resveratrol Motif for Synergetic Sonodynamic Therapy and Nuclear Factor Kappa B Transcription Suppression of Breast …

Y Li, M Sun, J Yu, W Jiang, W Tian… - Journal of Medicinal …, 2023 - ACS Publications
Sonodynamic therapy (SDT) has been recognized as a spatial–temporal and noninvasive
modality for the treatment of deep-seated tumors. However, current sonosensitizers suffer …

Jozimine A2, a Dimeric Naphthylisoquinoline (NIQ) Alkaloid, Shows In Vitro Cytotoxic Effects against Leukemia Cells through NF-κB Inhibition

R Damiescu, R Yücer, SM Klauck… - International Journal of …, 2024 - mdpi.com
Naphthylisoquinoline (NIQ) alkaloids are rising as a promising class of secondary
metabolites with pharmaceutical potential. NF-κB has already been recognized as a …

[HTML][HTML] Mechanism of Human Cytomegalovirus-Induced Epithelial–Mesenchymal Transition in Glioma Cells via the Upregulation of RIP2 Expression

K Cui, X Wang, CX Han, S Liu, Y Hu - Biological and Pharmaceutical …, 2023 - jstage.jst.go.jp
Human cytomegalovirus (HCMV) is associated with epithelial–mesenchymal transition
(EMT) in glioma cells; however, its underlying action mechanism remain ambiguous. In this …

Corema album Leaves Mediate DNA Damage in Triple-Negative Breast Cancer Cells

AS Cerquido, M Vojtek, R Ribeiro-Oliveira… - Current Issues in …, 2022 - mdpi.com
Corema (C.) album is a shrub endemic to the Atlantic coast and has been described as
yielding beneficial effects for human health. Nevertheless, studies concerning the bioactivity …

[HTML][HTML] SZC010 suppresses breast cancer development by regulating the PI3K/Akt/NF-κB signaling pathway

J Jiang, X Li, H Xu, Y Ma, M Fu, X Guo… - Chinese Clinical …, 2024 - cco.amegroups.org
Background: Breast cancer has become one of the leading causes of cancer deaths and is
the most frequently diagnosed cancer among females worldwide. Despite advances in …