Atherosclerosis: current pathogenesis and therapeutic options

C Weber, H Noels - Nature medicine, 2011 - nature.com
Coronary artery disease (CAD) arising from atherosclerosis is a leading cause of death and
morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism …

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

MJ Chapman, HN Ginsberg, P Amarenco… - European heart …, 2011 - academic.oup.com
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Carotid intima-media thickness progression as surrogate marker for cardiovascular risk: meta-analysis of 119 clinical trials involving 100 667 patients

P Willeit, L Tschiderer, E Allara, K Reuber… - Circulation, 2020 - Am Heart Assoc
Background: To quantify the association between effects of interventions on carotid intima-
media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk …

Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association

JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised …

C Baigent, MJ Landray, C Reith, J Emberson… - The Lancet, 2011 - thelancet.com
Background Lowering LDL cholesterol with statin regimens reduces the risk of myocardial
infarction, ischaemic stroke, and the need for coronary revascularisation in people without …

Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association

M Miller, NJ Stone, C Ballantyne, V Bittner, MH Criqui… - Circulation, 2011 - Am Heart Assoc
A long-standing association exists between elevated triglyceride levels and cardiovascular
disease*(CVD). 1, 2 However, the extent to which triglycerides directly promote CVD or …

Lipoprotein (a) as a cardiovascular risk factor: current status

BG Nordestgaard, MJ Chapman, K Ray… - European heart …, 2010 - academic.oup.com
Aims The aims of the study were, first, to critically evaluate lipoprotein (a)[Lp (a)] as a
cardiovascular risk factor and, second, to advise on screening for elevated plasma Lp (a), on …

Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association

LB Goldstein, CD Bushnell, RJ Adams, LJ Appel… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …

Secondary prevention after coronary artery bypass graft surgery: a scientific statement from the American Heart Association

A Kulik, M Ruel, H Jneid, TB Ferguson, LF Hiratzka… - Circulation, 2015 - Am Heart Assoc
The recommendations listed in this document are, whenever possible, evidence based.
Writing group members performed these relevant supplemental literature searches with key …

[HTML][HTML] Carotid-wall intima–media thickness and cardiovascular events

JF Polak, MJ Pencina, KM Pencina… - … England Journal of …, 2011 - Mass Medical Soc
Background Intima–media thickness of the walls of the common carotid artery and internal
carotid artery may add to the Framingham risk score for predicting cardiovascular events …