Disease and parasitism cause major welfare, environmental and economic concerns for
global aquaculture. In this review, we examine the status and potential of technologies that …

Pseudorabies virus (PRV) can infect most mammals and is well known for causing
substantial economic losses in the pig industry. In addition to pigs, PRV infection usually …

African swine fever (ASF) is a highly contagious, fatal disease of pigs caused by African
swine fever virus (ASFV). The complexity of ASFV and our limited understanding of its …

The advances in gene editing bring unprecedented opportunities in high throughput
functional genomics to animal research. Here we describe a genome wide CRISPR …

African swine fever virus (ASFV) is a lethal animal pathogen that enters its host cells through
endocytosis. So far, host factors specifically required for ASFV replication have been barely …

Our knowledge of the regulatory mechanisms that govern the replication of the rubella virus
(RV) in human cells is limited. To gain insight into the host-pathogen interaction, we …

The livestock industry is constantly threatened by viral disease outbreaks, including
infections with zoonotic potential. While preventive vaccination is frequently applied, disease …

The emergence of genome-scale forward genetic screening techniques, such as Haploid
Genetic screen and clustered regularly interspaced short palindromic repeats (CRISPR) …

Cellular sphingolipids have vital roles in human virus replication and spread as they are
exploited by viruses for cell entry, membrane fusion, genome replication, assembly …

The present study generated nectin1-mutant mice with single amino acid substitution and
tested the anti-pseudorabies virus (PRV) ability of the mutant mice, with the aim to establish …