Therapeutic applications of curcumin in diabetes: a review and perspective

C Quispe, J Herrera-Bravo, Z Javed… - BioMed Research …, 2022 - Wiley Online Library
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug
therapy as well as lifestyle changes. There is now growing scientific evidence to support the …

Absorption, distribution, metabolism, and excretion of US Food and Drug Administration–Approved antisense oligonucleotide drugs

JM Migliorati, S Liu, A Liu, A Gogate, S Nair… - Drug Metabolism and …, 2022 - ASPET
Absorption, distribution, metabolism, and excretion (ADME) are the key biologic processes
for determination of a drug's pharmacokinetic parameters, which have direct impacts on …

Physiology of the tongue with emphasis on taste transduction

ME Doyle, HU Premathilake, Q Yao… - Physiological …, 2023 - journals.physiology.org
The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

The molecular basis for zinc bioavailability

AG Hall, JC King - International journal of molecular sciences, 2023 - mdpi.com
Zinc is an essential micronutrient, and its deficiency is perhaps the most prevalent and least
understood worldwide. Recent advances have expanded the understanding of zinc's unique …

[HTML][HTML] Cardiac tissue engineering for myocardial infarction treatment

P Gil-Cabrerizo, I Scacchetti, E Garbayo… - European Journal of …, 2023 - Elsevier
Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …

Ingestible devices for long-term gastrointestinal residency: A review

MM Mau, S Sarker, BS Terry - Progress in Biomedical …, 2021 - iopscience.iop.org
Ingestible devices have been gaining attention from the medical community due to their
noninvasive use in diagnostics and treatment of the gastrointestinal (GI) tract. However, their …

Discovery of potential FGFR3 inhibitors via QSAR, pharmacophore modeling, virtual screening and molecular docking studies against bladder cancer

M Ganji, S Bakhshi, A Shoari… - Journal of Translational …, 2023 - Springer
Background Fibroblast growth factor receptor 3 is known as a favorable aim in vast range of
cancers, particularly in bladder cancer treatment. Pharmacophore and QSAR modeling …

Pleiotropic role of notch signaling in human skin diseases

R Gratton, PM Tricarico, C Moltrasio… - International journal of …, 2020 - mdpi.com
Notch signaling orchestrates the regulation of cell proliferation, differentiation, migration and
apoptosis of epidermal cells by strictly interacting with other cellular pathways. Any …

In vitro evaluation of bioavailability of Se from daily food rations and dietary supplements

P Bawiec, J Sawicki, P Łasińska-Pracuta, M Czop… - Nutrients, 2023 - mdpi.com
Bioavailability refers to a fraction of a substance that is potentially absorbed from the
gastrointestinal tract and enters the systemic circulation (blood). This term is related to …

Age and sex differences and temporal trends in the use of invasive and noninvasive procedures in patients hospitalized with acute myocardial infarction

VH Tran, J Mehawej, DM Abboud… - Journal of the …, 2022 - Am Heart Assoc
Background Few studies have examined age and sex differences in the receipt of cardiac
diagnostic and interventional procedures in patients hospitalized with acute myocardial …