Periodontal disease (PD) is a chronic inflammatory disease caused by the accumulation of
bacterial plaque biofilm on the teeth and the host immune responses. PD pathogenesis is …

Introduction. Chronic Periodontitis (CP) is suggested to be related to gene variations.
Present study aims to quantitatively estimate the association between interleukin‐6‐(IL‐6‐) …

Here we report an in-silico approach for identification, characterization and validation of
deleterious non-synonymous SNPs (nsSNPs) in the interleukin-8 gene using three steps. In …

Abstract Interleukin-8 (IL-8) gene polymorphisms have been considered as susceptibility
factors in periodontal disease. However, the functional roles of IL-8 gene haplotypes have …

Host genetic predispositions to dysregulated immune response can influence the
development of the aggressive form of periodontitis (AgP) through susceptibility to oral …

Objective The aim of the present study was to investigate the possible association between
seven Interleukin (IL) gene polymorphisms and their interaction with the chronic …

Interleukin‐17 contributes to the pathogenesis of type 1 diabetes mellitus (T1DM) and
chronic periodontitis (CP). We analyzed IL-17A− 197A/G and IL-17F+ 7488C/T …

Chronic periodontitis (CP) and diabetes mellitus (DM) involve several aspects of immune
functions, including neutrophil activity and cytokine biology. Considering the critical function …

Periodontal diseases are chronic infectious disease in which the pathogenic bacteria initiate
the host immune response leading to the destruction of tooth supporting tissue and …

Background Recent research is increasingly showing that host genetic variants can affect
the colonization by specific microbes. The aim of this study was to systematically investigate …