Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

AP Singh, A Biswas, A Shukla, P Maiti - Signal transduction and …, 2019 - nature.com
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …

Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic

A Puri, K Loomis, B Smith, JH Lee… - Critical Reviews™ in …, 2009 - dl.begellhouse.com
In recent years, various nanotechnology platforms in the area of medical biology, including
both diagnostics and therapy, have gained remarkable attention. Moreover, research and …

Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems

J Kuntsche, JC Horst, H Bunjes - International journal of pharmaceutics, 2011 - Elsevier
Cryogenic transmission electron microscopy (cryo-TEM) has evolved into an indispensable
tool for the characterization of colloidal drug delivery systems. It can be applied to study the …

Lipid nanoparticles for parenteral delivery of actives

MD Joshi, RH Müller - European journal of pharmaceutics and …, 2009 - Elsevier
The present review compiles the applications of lipid nanoparticles mainly solid lipid
nanoparticles (SLN), nanostructured lipid carriers (NLC) and lipid drug conjugates (LDC) in …

Solid lipid nanoparticles as vehicles of drugs to the brain: current state of the art

L Gastaldi, L Battaglia, E Peira, D Chirio… - European Journal of …, 2014 - Elsevier
Central nervous system disorders are already prevalent and steadily increasing among
populations worldwide. However, most of the pharmaceuticals present on world markets are …

Lipid-based nanoformulations in the treatment of neurological disorders

FH Pottoo, S Sharma, MN Javed, MA Barkat… - Drug Metabolism …, 2020 - Taylor & Francis
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …

Effects of quercetin loaded nanostructured lipid carriers on the paraquat-induced toxicity in human lymphocytes

E Ahmadian, A Eftekhari, T Kavetskyy… - Pesticide biochemistry …, 2020 - Elsevier
Paraquat (PQ) as a herbicide and an environmental pollutant with increasing importance
due to its toxicity to humans and animals. This study aimed to evaluate the protective and …

Challenges in the physical characterization of lipid nanoparticles

SS Hallan, M Sguizzato, E Esposito, R Cortesi - Pharmaceutics, 2021 - mdpi.com
Nano-sized drug transporters have become an efficient approach with considerable
commercial values. Nanomedicine is not only limited to drug delivery by means of different …