Activatable fluorescent probes for in situ imaging of enzymes

X Wu, R Wang, N Kwon, H Ma, J Yoon - Chemical Society Reviews, 2022 - pubs.rsc.org
As the main biomarkers of most diseases, enzymes play fundamental but extremely critical
roles in biosystems. High-resolution studies of enzymes using activatable in situ …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Activity-based sensing and theranostic probes based on photoinduced electron transfer

W Sun, M Li, J Fan, X Peng - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus Fluorescent probes have become powerful tools in detection, imaging and
disease diagnosis due to their high sensitivity, specificity, fast response, and technical …

Fluorescent probes for the selective detection of chemical species inside mitochondria

Z Xu, L Xu - Chemical Communications, 2016 - pubs.rsc.org
During the last few years, the preparation of novel fluorescent probes for the selective
detection of chemical species inside mitochondria has attracted considerable attention …

Size- and Wavelength-Dependent Two-Photon Absorption Cross-Section of CsPbBr3 Perovskite Quantum Dots

J Chen, K Zidek, P Chábera, D Liu… - The journal of …, 2017 - ACS Publications
All-inorganic colloidal perovskite quantum dots (QDs) based on cesium, lead, and halide
have recently emerged as promising light emitting materials. CsPbBr3 QDs have also been …

Molecular imaging: design mechanism and bioapplications

L Chen, Y Lyu, X Zhang, L Zheng, Q Li, D Ding… - Science China …, 2023 - Springer
Molecular imaging is a non-invasive method to image and analyze the concentration and
activity of functional biomolecules in cells or in vivo at molecular level, and plays an …

Leucine Aminopeptidase-Mediated Multifunctional Molecular Imaging Tool for Diagnosis, Drug Evaluation, and Surgical Guidance of Liver-Related Diseases

L Xu, M Ma, J Li, D Gao, P Ma, F Zhang… - Analytical …, 2023 - ACS Publications
Traditional molecular imaging tools used for detecting liver diseases own several
drawbacks, such as poor optical performance and limited applicability. Monitoring the …

A ratiometric fluorescent probe for monitoring leucine aminopeptidase in living cells and zebrafish model

Z Zhou, F Wang, G Yang, C Lu, J Nie, Z Chen… - Analytical …, 2017 - ACS Publications
Leucine aminopeptidase (LAP) is an important cancer-related biomarker, which shows
significant overexpression in malignant tumor cells like liver cancer. Developing an effective …

Design and application of lysosomal targeting pH-sensitive β-galactosidase fluorescent probe

S Chen, X Ma, L Wang, Y Wu, Y Wang, W Fan… - Sensors and Actuators B …, 2023 - Elsevier
Abstract β-galactosidase is a lysosomal enzyme that plays an essential biological function
as a cancer marker in many physiological and pathological processes. Therefore, it is of …

Probes for noninvasive biological visualization and biosensing of cancer cells

S Kadian, S Shukla, RJ Narayan - Applied Physics Reviews, 2023 - pubs.aip.org
The early detection of tumors and precancerous conditions is vital for cancer diagnosis.
Advances in fluorescence microscopic techniques and materials synthesis processes have …