Serum troponins as biomarkers of drug-induced cardiac toxicity

KB Wallace, E Hausner, E Herman… - Toxicologic …, 2004 - journals.sagepub.com
BACKGROUND OF THE EWG The Expert Working Group (EWG) on Biomarkers of Drug-
Induced Cardiac Toxicity was established as a factfinding working group to the Nonclinical …

Degradation of cardiac troponin I: implication for reliable immunodetection

AG Katrukha, AV Bereznikova, VL Filatov… - Clinical …, 1998 - academic.oup.com
We have analyzed by different immunological methods the proteolytic degradation of
cardiac troponin I (cTnI) in human necrotic tissue and in serum. cTnI is susceptible to …

Elevated circulating cardiac troponin I in patients with cirrhosis

D Pateron, P Beyne, T Laperche, D Logeard… - Hepatology, 1999 - journals.lww.com
It has been shown that certain patients with cirrhosis have asymptomatic cardiac
abnormalities that have not yet been explained. Thus, cardiac troponin I, a specific marker of …

Discordance between results for serum troponin T and troponin I in renal disease

V Bhayana, T Gougoulias, S Cohoe… - Clinical …, 1995 - academic.oup.com
Two patients were investigated for unexplained increases in troponin T. In the first patient,
who had rhabdomyolysis and acute renal failure, troponin T reached a peak value of 13.50 …

Cardiac troponin I measurement with the ACCESS® immunoassay system: analytical and clinical performance characteristics

RH Christenson, FS Apple, DL Morgan… - Clinical …, 1998 - academic.oup.com
We evaluated the ACCESS® cardiac troponin I (cTnI) immunoassay as a marker for
myocardial infarction (MI). Total imprecision was 6.0% to 13.5%, the minimum detectable …

Estimation of postmortem interval using the protein marker cardiac Troponin I

AJ Sabucedo, KG Furton - Forensic science international, 2003 - Elsevier
The importance of determining the time since death is crucial to criminal, civil and forensic
cases. A technique exploiting the degradation of a protein, cardiac Troponin I (cTnI), to …

Cardiac troponin I in diagnosis of perioperative myocardial infarction after cardiac surgery

MA Alyanakian, M Dehoux, D Chatel, C Seguret… - Journal of cardiothoracic …, 1998 - Elsevier
Objective: The diagnosis of perioperative myocardial infarction (PMI) after cardiac surgery
remains an important issue. The present study was designed to determine the relevance of …

Cardioprotective activity of melatonin and its novel synthesized derivatives on doxorubicin-induced cardiotoxicity

HH Ahmed, F Mannaa, GA Elmegeed… - Bioorganic & medicinal …, 2005 - Elsevier
This study aimed at evaluation of melatonin and some of its novel synthesized derivatives 3,
4, 9 and 10b as cardioprotective agents against doxorubicin-induced acute cardiac toxicity …

The role of cardiac troponin‐I (cTnI) in risk stratification of patients with unstable coronary artery disease

MJ Tanasijevic, CP Cannon, EM Antman - Clinical cardiology, 1999 - Wiley Online Library
In patients with chest pain at rest but no ST‐segment elevation on the electrocardiogram, the
diagnoses of unstable angina and non‐Q‐wave myocardial infarction (MI) are usually …

[HTML][HTML] Effect of recent cocaine use on the specificity of cardiac markers for diagnosis of acute myocardial infarction

JE Hollander, MA Levitt, GP Young, E Briglia… - American heart …, 1998 - Elsevier
We evaluated whether recent cocaine use alters the specificity of CK-MB, myoglobin, and
cardiac troponin I for acute myocardial infarction (AMI) in patients who are seen in the …