Alterations in cardiac energy metabolism contribute to the severity of heart failure. However,
the energy metabolic changes that occur in heart failure are complex and are dependent not …

Obesity continues to be among the top health concerns across the globe. Despite our failure
to contain the high prevalence of obesity, we now have a better understanding of its …

The past 3 decades have been characterized by an exponential growth in knowledge and
advances in the clinical treatment of atrial fibrillation (AF). It is now known that AF genesis …

Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD)
morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage …

Background: Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …

The prevalence of obesity has increased worldwide and is a source of concern since the
negative consequences of obesity start as early as in childhood. The most commonly used …

Aim We tested the hypothesis that dapagliflozin may regress left ventricular hypertrophy
(LVH) in people with type 2 diabetes (T2D). Methods and results We randomly assigned 66 …

Obesity produces a variety of hemodynamic alterations that may cause changes in cardiac
morphology which predispose to left and right ventricular dysfunction. Various …

Obesity has reached epidemic proportions in the United States and worldwide. Considering
the adverse effects of obesity on left ventricular (LV) structure, diastolic and systolic function …

Obesity is now so common within the world's population that it is beginning to replace
undernutrition and infectious diseases as the most significant contributor to ill health. In …