Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological
disorders, with a high mortality rate and severe disabling functional sequelae. Systemic …

Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease
(PD), are severe age-related disorders with complex and multifactorial causes. Recent …

Current COVID-19 pandemic poses an unprecedented threat to global health and
healthcare systems. The most amount of the death toll is accounted by old people affected …

Background Retinitis pigmentosa is a rod-cone degenerative disease that induces
irreversible vision loss. This study probed the protective capacity of mesenchymal stem cell …

Inflammation is a key factor in the pathogenesis of dry eye disease (DED). We aimed to
investigate the role of microRNA-146a (miR-146a) in regulating corneal inflammation in a …

As an integral part of the innate immune system of the brain, resident microglia must react
rapidly to the onset of brain injury and neurological disease. These dynamic cells then …

Background MiRNA-146a and miRNA-223 are key epigenetic regulators of toll-like receptor
4 (TLR4)/tumor necrosis factor-receptor-associated factor 6 (TRAF6)/NOD-like receptor …

Aims: Metabolic disorders may play key roles in oxidative stress and neuronal apoptosis in
response to early brain injury (EBI) after subarachnoid hemorrhage (SAH). Pyruvate …

Abstract Alzheimer's Disease (AD), a multifaceted neurodegenerative disorder, is
increasingly understood through the regulatory lens of microRNAs (miRNAs). This review …

A diabetic wound is a refractory disease that afflicts patients globally. MicroRNA-146a-5p
(miR-146a-5p) is reported to represent a potential therapeutic target for diabetic wounds …