[HTML][HTML] Beyond the barriers of light penetration: strategies, perspectives and possibilities for photodynamic therapy

S Mallidi, S Anbil, AL Bulin, G Obaid, M Ichikawa… - Theranostics, 2016 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a photochemistry based treatment modality that involves the
generation of cytotoxic species through the interactions of a photosensitizer molecule with …

Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success

BW Pogue, JT Elliott, SC Kanick… - Physics in Medicine …, 2016 - iopscience.iop.org
Photodynamic therapy (PDT) can be a highly complex treatment, with many parameters
influencing treatment efficacy. The extent to which dosimetry is used to monitor and …

Near-infrared absorbing Ru (ii) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma

LM Lifshits, JA Roque III, P Konda, S Monro… - Chemical …, 2020 - pubs.rsc.org
Mounting evidence over the past 20 years suggests that photodynamic therapy (PDT), an
anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic …

Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates …

G Obaid, S Bano, S Mallidi, M Broekgaarden… - Nano …, 2019 - ACS Publications
Despite untiring efforts to develop therapies for pancreatic ductal adenocarcinoma (PDAC),
survival statistics remain dismal, necessitating distinct approaches. Photodynamic priming …

A GSH-activatable ruthenium (ii)-azo photosensitizer for two-photon photodynamic therapy

L Zeng, S Kuang, G Li, C Jin, L Ji… - Chemical Communications, 2017 - pubs.rsc.org
A glutathione (GSH)-activatable ruthenium (II)-azo photosensitizer was prepared. The
complex had low toxicity towards cells under dark conditions. It exhibited excellent …

A combination of visudyne and a lipid‐anchored liposomal formulation of benzoporphyrin derivative enhances photodynamic therapy efficacy in a 3D model for …

I Rizvi, S Nath, G Obaid, MK Ruhi… - Photochemistry and …, 2019 - Wiley Online Library
A major objective in developing new treatment approaches for lethal tumors is to reduce
toxicity to normal tissues while maintaining therapeutic efficacy. Photodynamic therapy …

Clinical application of photodynamic diagnosis and photodynamic therapy for gynecologic malignant diseases: A review

Y Matoba, K Banno, I Kisu, D Aoki - Photodiagnosis and photodynamic …, 2018 - Elsevier
Introduction Several types of photosensitizers such as 5-aminolevulinic acid are progenitors
of protoporphyrin IX (PpIX). PpIX accumulates in cancer cells and has photosensitivity …

Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor …

J Hempstead, DP Jones, A Ziouche, GM Cramer… - Scientific reports, 2015 - nature.com
A lack of access to effective cancer therapeutics in resource-limited settings is implicated in
global cancer health disparities between developed and developing countries …

Photodynamic therapy in 3D cancer models and the utilisation of nanodelivery systems

L Mohammad-Hadi, AJ MacRobert, M Loizidou… - Nanoscale, 2018 - pubs.rsc.org
Photodynamic therapy (PDT) is the subject of considerable research in experimental cancer
models mainly for the treatment of solid cancerous tumours. Recent studies on the use of …

Photodynamic therapy monitoring with optical coherence angiography

MA Sirotkina, LA Matveev, MV Shirmanova… - Scientific reports, 2017 - nature.com
Photodynamic therapy (PDT) is a promising modern approach for cancer therapy with low
normal tissue toxicity. This study was focused on a vascular-targeting Chlorine E6 mediated …