Covering 2000 to June 2015 This review discusses the biosynthesis of natural products that
are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes …

Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive”
intermediates, or even as a “synthetic enigma” in organic chemistry. Indeed, there were just …

para‐Quinone methides (p‐QMs) are naturally occurring molecules that have been finding
increasing synthetic applications in the last few years. The presence of two electronically …

Presented is the first enantioselective copper‐catalyzed 1, 6‐conjugate addition of bis
(pinacolato) diboron to para‐quinone methides. The reaction proceeds with excellent yields …

Wen-Dao Chu, Le-Fen Zhang, Xu Bao, Xian-He Zhao, Chao Zeng, Ji-Yuan Du, Guo-Biao
Zhang, Fang-Xin Wang, Xiao-Yan Ma, and Chun-An Fan* para-Quinone methides [p-QMs; …

Described herein is a general and mild catalytic asymmetric 1, 6‐conjugate addition of para‐
quinone methides (p‐QMs), a class of challenging reactions with previous limited success …

In the last few years, there has been an explosive growth in the area of para‐quinone
methide (p‐QM) chemistry. This boom is actually due to the unique reactivity pattern of p …

The organocatalytic asymmetric α-alkylation of aldehydes by 1, 6-conjugated addition of
enamines to p-quinone methides is described. Employing a newly developed class of chiral …

A new sheriff in town: para‐Quinone methides (p‐QMs) have been successfully used in
asymmetric organocatalysis. Particularly, the asymmetric 1, 6‐addition of phenyl malonate …

Abstract An asymmetric 1, 6‐conjugate addition of thioacetic acid with para‐quinone
methides has been developed by using chiral phosphoric acid catalysis in the presence of …