Epidemiology, implications and mechanisms underlying drug-induced weight gain in psychiatric patients

U Zimmermann, T Kraus, H Himmerich, A Schuld… - Journal of psychiatric …, 2003 - Elsevier
Body weight gain frequently occurs during drug treatment of psychiatric disorders and is
often accompanied by increased appetite or food craving. While occurrence and time course …

Cytokines in schizophrenia and the effects of antipsychotic drugs

Ł Drzyzga, E Obuchowicz, A Marcinowska… - Brain, behavior, and …, 2006 - Elsevier
Growing evidence suggests that the immune, endocrine, and nervous systems interact with
each other through cytokines, hormones, and neurotransmitters. The activation of the …

Almost all antipsychotics result in weight gain: a meta-analysis

M Bak, A Fransen, J Janssen, J van Os, M Drukker - PloS one, 2014 - journals.plos.org
Introduction Antipsychotics (AP) induce weight gain. However, reviews and meta-analyses
generally are restricted to second generation antipsychotics (SGA) and do not stratify for …

[图书][B] The Maudsley prescribing guidelines

D Taylor, C Paton - 2009 - taylorfrancis.com
One of the most widely used guides to prescribing psychiatric medications, the Tenth Edition
of Maudsley Prescribing Guidelines returns with fully updated content and new sections on …

Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal …

DC Henderson, E Cagliero, PM Copeland… - Archives of general …, 2005 - jamanetwork.com
Background While the incidence of new-onset diabetes mellitus may be increasing in
patients with schizophrenia treated with certain atypical antipsychotic agents, it remains …

Adverse metabolic effects associated with atypical antipsychotics: literature review and clinical implications

K Melkersson, ML Dahl - Drugs, 2004 - Springer
Adverse metabolic effects, such as diabetes mellitus, lipid abnormalities and weight gain,
have increasingly been recognised with the use of the newer, so-called atypical …

Obesity and related metabolic abnormalities during antipsychotic drug administration: mechanisms, management and research perspectives

T Baptista, N Kin, S Beaulieu… - …, 2002 - thieme-connect.com
Excessive body weight gain (BWG) is a common side effect of some typical and atypical
antipsychotic drugs (APs). Convergent evidence suggests a hierarchy in the magnitude of …

Effects of antipsychotics on fat deposition and changes in leptin and insulin levels: magnetic resonance imaging study of previously untreated people with …

ZJ Zhang, ZJ Yao, WEN Liu, QUN Fang… - The British journal of …, 2004 - cambridge.org
BackgroundWeight gain is a common consequence of antipsychotic drug treatment and can
lead to further morbidity. AimsTo assess the effects of antipsychotic drug therapy on …

Atypical antipsychotic-induced weight gain: insights into mechanisms of action

JL Roerig, KJ Steffen, JE Mitchell - CNS drugs, 2011 - Springer
Prescriptions for second-generation antipsychotics (SGAs) have surpassed those for first-
generation agents in the treatment of schizophrenia and bipolar disorder. While SGAs have …

Serum leptin and triglyceride levels in patients on treatment with atypical antipsychotics

M Atmaca, M Kuloglu, E Tezcan… - Journal of Clinical …, 2003 - psychiatrist.com
Background: Weight gain is a common adverse effect associated with the use of most
antipsychotic drugs. Leptin has been reported to be associated with antipsychotic-induced …