Impacts of oxidative stress and PI3K/AKT/mTOR on metabolism and the future direction of investigating fucoidan-modulated metabolism

JP Shiau, YT Chuang, YB Cheng, JY Tang, MF Hou… - Antioxidants, 2022 - mdpi.com
The critical factors for regulating cancer metabolism are oxidative stress and
phosphoinositide-3-kinase/AKT serine-threonine kinase/mechanistic target of the rapamycin …

[HTML][HTML] Phlorofucofuroeckol-A refined by edible brown algae Ecklonia cava indicates anti-inflammatory effects on TNF-α/IFN-γ-stimulated HaCaT keratinocytes and …

KGIS Kirindage, AMK Jayasinghe, EJ Han… - Journal of Functional …, 2023 - Elsevier
The present study investigated the anti-inflammatory potential of phlorofucofuroeckol-A (PFF-
A) from Ecklonia cava in TNF-α/IFN-γ-stimulated HaCaT keratinocytes and an acute ear …

[HTML][HTML] The structural characteristics, biological activities and mechanisms of bioactive brown seaweed polysaccharides: A review

QL Zhou, Z Wang, WT Chen, XF Liu, KL Cheong… - Journal of Functional …, 2024 - Elsevier
Brown seaweed polysaccharides (BSPs) are potential alternative sources of bioactive
compounds. The food and pharmaceutical industries have a great interest in BSPs because …

The Anti-Inflammatory Effect of Low Molecular Weight Fucoidan from Sargassum siliquastrum in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via …

AMK Jayasinghe, KGIS Kirindage, IPS Fernando… - Marine Drugs, 2023 - mdpi.com
Brown seaweed is a rich source of fucoidan, which exhibits a variety of biological activities.
The present study discloses the protective effect of low molecular weight fucoidan (FSSQ) …

[HTML][HTML] Enhanced skin anti-inflammatory and moisturizing action of gold nanoparticles produced utilizing Diospyros kaki fruit extracts

S Dhandapani, R Wang, K cheol Hwang, H Kim… - Arabian Journal of …, 2023 - Elsevier
Inflammatory skin diseases (ISD) cause very severe itchy skin and dryness which is now a
days an important issue which has to be taken care. Nanotechnology plays a main role in …

Fucosterol Isolated from Dietary Brown Alga Sargassum horneri Protects TNF-α/IFN-γ-Stimulated Human Dermal Fibroblasts Via Regulating Nrf2/HO-1 and NF-κB …

KGIS Kirindage, AMK Jayasinghe, EJ Han, Y Jee… - Antioxidants, 2022 - mdpi.com
Sargassum horneri is a well-known edible brown alga that is widely abundant in the sea
near China, Korea, and Japan and has a wide range of bioactive compounds. Fucosterol …

Periplaneta americana extract incorporated silk fibroin nanofiber mat: A potential antioxidant dressing for wound healing

S Gao, X Xiong, H Xie, P Li, F Kong, Y Fan, S Meng… - Process …, 2023 - Elsevier
Although great progress has been made in cutaneous wound care, easily fabricated wound
dressings with optional biocompatibility and wound-healing efficiency. In present study, a …

Fucoidan refined from Saccharina japonica ameliorates ambient particulate matter-induced inflammation in keratinocytes, underlying fibroblasts, and 12-O …

KGIS Kirindage, AMK Jayasinghe, NK Cho… - International Journal of …, 2024 - Elsevier
Fucoidan from Saccharina japonica (SJF) was isolated and characterized, and its anti-
inflammatory effects on fine dust/ambient particulate matter (PM)-stimulated HaCaT …

ACSL4 is overexpressed in psoriasis and enhances inflammatory responses by activating ferroptosis

L Liu, X Kang - Biochemical and Biophysical Research …, 2022 - Elsevier
More and more studies have shown that ferroptosis is closely related to the progression of
various diseases, but the significance of ferroptosis in psoriasis is still rarely explored. The …

3-Bromo-4,5-dihydroxybenzaldehyde Isolated from Polysiphonia morrowii Suppresses TNF-α/IFN-γ-Stimulated Inflammation and Deterioration of Skin Barrier in …

AMK Jayasinghe, EJ Han, KGIS Kirindage… - Marine Drugs, 2022 - mdpi.com
Polysiphonia morrowii is a well-known red alga that has promising pharmacological
characteristics. The current study evaluates the protective effect of 3-bromo-4, 5 …