Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …

Microencapsulation is a promising strategy to prolong the survival and function of
transplanted pancreatic islets for diabetes therapy, albeit its translation has been impeded …

Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe
host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding …

Type 1 Diabetes Mellitus (T1DM) is characterized by the autoimmune destruction of β-cells
in the pancreatic islets. In this regard, islet transplantation aims for the replacement of the …

Immunoisolation of pancreatic islets is a technology in which islets are encapsulated in
semipermeable but immunoprotective polymeric membranes. The technology allows for …

Islet transplantation is a promising long-term, compliance-free, complication-preventing
treatment for type 1 diabetes. However, islet transplantation is currently limited to a narrow …

As a new group of anticancer drugs, immune checkpoint inhibitors (ICIs) have exhibited
favorable antitumor efficacy in numerous malignant tumors. Anti-cytotoxic T lymphocyte …

Brain organoid is a promising technique with potential applications in developmental study,
drug discovery and regenerative medicine, however, its practical values are restricted by …

Islet transplantation provides a promising strategy in treating type 1 diabetes as an
autoimmune disease, in which damaged β-cells are replaced with new islets in a minimally …