The logical (or logic) formalism is increasingly used to model regulatory and signaling
networks. Complementing these applications, several groups contributed various methods …

Quantitative systems pharmacology (QSP) is an emerging discipline that aims to discover
how drugs modulate the dynamics of biological components in molecular and cellular …

Predicting biological systems' behaviors requires taking into account many molecular and
genetic elements for which limited information is available past a global knowledge of their …

Purpose: We put forward a theoretical and dynamical approach for the semi-quantitative
analysis of CD4+ T cell differentiation, the process by which cells with different functions are …

Computational modeling constitutes a crucial step toward the functional understanding of
complex cellular networks. In particular, logical modeling has proven suitable for the …

Terminal differentiation of B cells is an essential process for the humoral immune response
in vertebrates and is achieved by the concerted action of several transcription factors in …

It is coming nowadays more clear that in order to obtain a unified description of the different
mechanisms governing the behavior and causality relations among the various parts of a …

T CD4+ cells are central to the adaptive immune response against pathogens. Their
activation is induced by the engagement of the T-cell receptor by antigens, and of co …

Boolean networks are commonly used in systems biology to model dynamics of biochemical
networks by abstracting away many (and often unknown) parameters related to speed and …

In this paper, two pinning control (PC) schemes are proposed to achieve non-periodical
stable behaviors for asynchronous Boolean networks (BNs), from the aspects of state …