Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review

MT Di Martino, M Arbitrio, D Caracciolo… - … Therapy-Nucleic Acids, 2022 - cell.com
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

Mechanisms regulating glioma invasion

I Paw, RC Carpenter, K Watabe, W Debinski, HW Lo - Cancer letters, 2015 - Elsevier
Glioblastoma (GBM) is the most aggressive, deadliest, and most common brain malignancy
in adults. Despite the advances made in surgical techniques, radiotherapy and …

Gas5 exerts tumor-suppressive functions in human glioma cells by targeting miR-222

X Zhao, P Wang, J Liu, J Zheng, Y Liu, J Chen, Y Xue - Molecular Therapy, 2015 - cell.com
Aberrant expression of noncoding RNAs in glioma cells, including long noncoding RNAs
(lncRNAs) and microRNAs, may participate in the progression of glioma. Encoded by …

Liquid biopsy in glioblastoma management: from current research to future perspectives

L Gatto, E Franceschi, V Di Nunno, A Tosoni… - The …, 2021 - academic.oup.com
Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …

MicroRNAs in glioblastoma pathogenesis and therapy: A comprehensive review

BK Ahir, H Ozer, HH Engelhard, SS Lakka - Critical Reviews in Oncology …, 2017 - Elsevier
Glioblastoma (GBM), also known as grade IV astrocytoma, is the most aggressive primary
intracranial tumor of the adult brain. MicroRNAs (miRNAs), a class of small non-coding RNA …

Self-functionalized superlattice nanosensor enables glioblastoma diagnosis using liquid biopsy

S Premachandran, R Haldavnekar, S Ganesh, S Das… - ACS …, 2023 - ACS Publications
Glioblastoma (GBM), the most aggressive and lethal brain cancer, is detected only in the
advanced stage, resulting in a median survival rate of 15 months. Therefore, there is an …

Glioma stem cells and their microenvironments: providers of challenging therapeutic targets

E Codrici, AM Enciu, ID Popescu, S Mihai… - Stem cells …, 2016 - Wiley Online Library
Malignant gliomas are aggressive brain tumors with limited therapeutic options, possibly
because of highly tumorigenic subpopulations of glioma stem cells. These cells require …

Emerging roles of ferroptosis-related miRNAs in tumor metastasis

Z Jiang, J Zhou, J Deng, L Li, R Wang, Y Han… - Cell death …, 2023 - nature.com
Ferroptosis, a novel mode of cell death dependent on iron and reactive oxygen species, has
been extensively explored during malignant tumors metastasis. Ferroptosis can interact with …