The rejection of process impurities from crystallizing products is an essential step for the
purification of pharmaceutical drugs and for the isolation of active pharmaceutical …

The thermodynamic relationship between FI and FII of ethyl 4-aminobenzoate (benzocaine)
has been investigated. Slurry conversion experiments show that the transition temperature …

Benzocaine (BZC), an efficient and highly permeable anaesthetic and an active
pharmaceutical ingredient of many commercially available drugs, was studied under high …

It is important to quantify amorphous solid in active pharmaceutical ingredients (API) of
formulations to guarantee high-quality pharmaceutical products. In this study, we aimed to …

Excipients are crucial components of most pharmaceutical formulations. In the case of a
solid oral dosage formulation containing the salt form of a weakly ionizable drug, excipient …

The availability of sufficient amounts of form I of benzocaine has led to the investigation of its
phase relationships with the other two existing forms, II and III, using adiabatic calorimetry …

Salt disproportionation is a major issue for pharmaceutical products containing a salt form of
a weakly basic drug, because conversion to the free base during processing or storage in …

The crystal structures of two intermediates, 4-amino-3, 5-difluorobenzonitrile, C7H4F2N2 (I),
and ethyl 4-amino-3, 5-difluorobenzoate, C9H9F2NO2 (II), along with a visible-light …

Solid solutions of aripiprazole (APZ) and its active metabolite, dehydro-aripiprazole (dAPZ),
have been prepared as free form (neat or nonsolvated), hydrated, or alcohol-solvated …

The availability of sufficient amounts of form I of benzocaine has led to the investigation of its
phase relationships with the other two existing forms, II and III, using adiabatic calorimetry …