The microtubule minus-end-directed motility of cytoplasmic dynein 1 (dynein), arguably the
most complex and versatile cytoskeletal motor, is harnessed for diverse functions, such as …

Dynein, an ancient microtubule-based motor protein, performs diverse cellular functions in
nearly all eukaryotic cells, with the exception of land plants. It has evolved into three …

Error-free chromosome segregation in mitosis and meiosis relies on the assembly of a
microtubule-based spindle that interacts with kinetochores to guide chromosomes to the cell …

The microtubule motor dynein plays a key role in cellular organization. However, little is
known about how dynein's biosynthesis, assembly, and functional diversity are orchestrated …

Cytoplasmic dynein-driven movement of chromosomes during prophase I of mammalian
meiosis is essential for synapsis and genetic exchange. Dynein connects to chromosome …

The dynein motor performs multiple functions in mitosis by engaging with a wide cargo
spectrum. One way to regulate dynein's cargo-binding selectivity is through the C-terminal …

Dynein, a homodimeric protein complex, plays a pivotal role in retrograde transportation
along microtubules within cells. It consists of various subunits, among which the light …

In elaborating and maintaining myelin sheaths on multiple axons/segments,
oligodendrocytes distribute translation of some proteins, including myelin basic protein …

OFD1 is a protein involved in many cellular processes, including cilia biogenesis, mitotic
spindle assembly, translation, autophagy and the repair of double-strand DNA breaks …

Background The motor protein dynein is integral to retrograde transport along microtubules
and interacts with numerous cargoes through the recruitment of cargo‐specific adaptor …