Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

A sensitive and accurate imaging technique capable of tracking the disease progression of
Alzheimer's Disease (AD) driven amnestic dementia would be beneficial. A currently …

Microglia are necessary for central nervous system (CNS) function during development and
play roles in ageing, Alzheimer's disease and the response to demyelinating injury,,,–. The …

Purpose A method named DECOMPOSE-QSM is developed to decompose bulk
susceptibility measured with QSM into sub-voxel paramagnetic and diamagnetic …

MRI has been widely used to probe the neuroanatomy of the mouse brain, directly
correlating MRI findings to histology is still challenging due to the limited spatial resolution …

Concussion or mild traumatic brain injury is the most common form of traumatic brain injury
with potentially long-term consequences. Current objective diagnosis and treatment options …

The aim of this study was to investigate the mechanisms underlying demyelination and
remyelination with 7.0 T multiparameter magnetic resonance imaging (MRI) in an alternative …

Objective To investigate the influences of the diffusion gradient directions (angular
resolution) and the strength of the diffusion gradient (b value) on diffusion tensor imaging …

Purpose The aim of this study was to investigate alterations in white matter lesions (WMLs)
and normal-appearing white matter (NAWM) with small vessel disease (SVD) over 1–2 …

Abstract Neurodegenerative disorders, including Multiple Sclerosis (MS), are heterogenous
disorders which affect the myelin sheath of the central nervous system (CNS). Magnetic …