Abstract β-tricalcium phosphate (β-TCP) is one the most used and potent synthetic bone
graft substitute. It is not only osteoconductive, but also osteoinductive. These properties …

Bone healing is an impressive ability of the human body, but critical-sized bone defects
require external intervention. Bioceramic scaffolds with excellent biocompatibility and …

Recently, the fabrication methods of orthopedic implants and devices have been greatly
developed. Additive manufacturing technology allows the production of complex structures …

Toward the aim of personalized treatment, three-dimensional (3D) printing technology has
been widely used in bone tissue engineering owing to its advantage of a fast, precise, and …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Chitin is one of the most abundant polysaccharide found on earth. The deacetylated form of
chitin viz. chitosan has been reported for its various important pharmacological properties …

As a kind of smart material, shape memory polymer (SMP) shows great application potential
in the biomedical field. Compared with traditional metal‐based medical devices, SMP …

Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …