Cryopreservation of ovarian tissue to preserve the fertility of girls and young women at high risk of sterility is now widely practiced. Pieces of cryopreserved ovarian cortex can be …
STUDY QUESTION Can complete oocyte development be achieved from human ovarian tissue containing primordial/unilaminar follicles and grown in vitro in a multi-step culture to …
L Kalich-Philosoph, H Roness, A Carmely… - Science translational …, 2013 - science.org
Premature ovarian failure and infertility are major side effects of chemotherapy treatments in young cancer patients. A more thorough understanding of the mechanism behind …
BACKGROUND Advanced maternal age is associated with reduced fertility and adverse pregnancy outcomes. This review details recent developments in our understanding of the …
EE Telfer, MB Zelinski - Fertility and sterility, 2013 - Elsevier
The removal and cryostorage of ovarian cortical biopsies is now offered as a fertility preservation option for young women. The only available option to restore fertility using this …
A Makker, MM Goel, AA Mahdi - Journal of molecular …, 2014 - jme.bioscientifica.com
The α and β cells act in concert to maintain blood glucose. The α cells release glucagon in response to low levels of glucose to stimulate glycogenolysis in the liver. In contrast, β cells …
J Roa, M Tena-Sempere - Molecular and cellular endocrinology, 2014 - Elsevier
It is well established that pubertal activation of the reproductive axis and maintenance of fertility are critically dependent on the magnitude of body energy reserves and the metabolic …
R Rosario, HL Stewart, N Spears, EE Telfer… - Human …, 2024 - academic.oup.com
STUDY QUESTION What are the effects of cyclophosphamide exposure on the human ovary and can anti-Mullerian hormone (AMH) and rapamycin protect against these? SUMMARY …
EE Telfer - Acta obstetricia et gynecologica Scandinavica, 2019 - Wiley Online Library
Removal and storage of ovarian cortical tissue is currently offered to young female cancer patients undergoing potentially sterilizing chemotherapy and/or radiotherapy. For patients at …