β-glucan induces distinct and protective innate immune memory in differentiated macrophages

CL Stothers, KR Burelbach, AM Owen… - The Journal of …, 2021 - journals.aai.org
Bacterial infections are a common and deadly threat to vulnerable patients. Alternative
strategies to fight infection are needed. β-Glucan, an immunomodulator derived from the …

Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway

H Sun, C Tang, SH Chung, XQ Ye, Y Makusheva… - Cell reports, 2022 - cell.com
Dendritic cell immunoreceptor (DCIR; Clec4a2), a member of the C-type lectin receptor
family, plays important roles in homeostasis of the immune and bone systems. However, the …

[HTML][HTML] Synthesis and study of antifungal properties of new cationic beta-glucan derivatives

K Kaminski, M Skora, P Krzyściak, S Stączek… - Pharmaceuticals, 2021 - mdpi.com
The interaction of positively charged polymers (polycations) with a biological membrane is
considered to be the cause of the frequently observed toxicity of these macromolecules. If it …

Nucleic acid sensing Toll-like receptors 3 and 9 play complementary roles in the development of bacteremia after nasal colonization associated with influenza co …

D Nanushaj, M Kono, H Sakatani, D Murakami… - Experimental …, 2024 - jstage.jst.go.jp
Streptococcus pneumoniae can cause mortality in infant, elderly, and immunocompromised
individuals owing to invasion of bacteria to the lungs, the brain, and the blood. In building …

The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability …

Y Makusheva, SH Chung, A Akitsu, N Maeda… - Experimental …, 2022 - jstage.jst.go.jp
Clec1A, a member of C-type lectin receptor family, has a carbohydrate recognition domain in
its extracellular region, but no known signaling motif in the cytoplasmic domain. Clec1a is …

Diagnostic Challenge and Therapeutic Approaches in Human Sepsis Based on the Appearance of Endotoxemia and Beta-d-Glucanemia

H Tamura, Y Adachi - International Journal of Molecular Sciences, 2021 - mdpi.com
Circulating endotoxin, also called lipopolysaccharide (LPS) and (1→ 3)-β-D-Glucan (β-D-
glucan), major constituents of bacterial and fungal cell walls, respectively, are determined as …

[引用][C] Yeast β-glucan increases etoposide sensitivity in lung cancer cell line A549 by suppressing nuclear factor erythroid 2-related factor 2 via the noncanonical …

FM Siswanto, A Tamura, R Sakuma, S Imaoka - Molecular Pharmacology, 2022 - ASPET