Do antibiotics maintain antibiotic resistance?

JA Heinemann, RG Ankenbauer… - Drug discovery today, 2000 - Elsevier
Important human pathogens resistant to antibiotics result from the human use of antibiotics.
Does this imply that reducing their usage or removing antibiotics from medicine and …

[HTML][HTML] Optimal use of antibiotic resistance surveillance systems

IA Critchley, JA Karlowsky - Clinical microbiology and infection, 2004 - Elsevier
Increasing concern about the emergence of resistance in clinically important pathogens has
led to the establishment of a number of surveillance programmes to monitor the true extent …

From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathways

SY Gerdes, MD Scholle, M D'Souza, A Bernal… - 2002 - Am Soc Microbiol
Novel drug targets are required in order to design new defenses against antibiotic-resistant
pathogens. Comparative genomics provides new opportunities for finding optimal targets …

[图书][B] Medicinal chemistry: a molecular and biochemical approach

T Nogrady, DF Weaver - 2005 - books.google.com
Fully updated and rewritten by a basic scientist who is also a practicing physician, the third
edition of this popular textbook remains comprehensive, authoritative and readable. Taking …

Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin‐resistant bacteria: target‐accelerated combinatorial synthesis

KC Nicolaou, R Hughes, SY Cho… - … A European Journal, 2001 - Wiley Online Library
Based on the notion that dimerization and/or variation of amino acid 1 of vancomycin could
potentially enhance biological activity, a series of synthetic and chemical biology studies …

An array of target-specific screening strains for antibacterial discovery

JA DeVito, JA Mills, VG Liu, A Agarwal… - nature …, 2002 - nature.com
As the global threat of drug-and antibiotic-resistant bacteria continues to rise, new strategies
are required to advance the drug discovery process. This work describes the construction of …

Genomics and future biological weapons: the need for preventive action by the biomedical community

CM Fraser, MR Dando - Nature genetics, 2001 - nature.com
There is an increasing concern within both the scientific and security communities that the
ongoing revolution in biology has great potential to be misused in offensive biological …

Host–guest interaction driven peptide assembly into photoresponsive two-dimensional nanosheets with switchable antibacterial activity

X Xie, B Gao, Z Ma, J Liu, J Zhang, J Liang… - CCS …, 2021 - chinesechemsoc.org
Selectively controlling the bioactivity of antimicrobial peptides is not only a fascinating
scientific challenge but also a necessity in localized antibacterial therapy. Here, a smart …

In silico identification of candidate drug and vaccine targets from various pathways in Neisseria gonorrhoeae

D Barh, A Kumar - In silico biology, 2009 - content.iospress.com
Neisseria gonorrhoeae is responsible for causing gonorrhea, one of the most common
sexually transmitted diseases prevailing globally. Although extensive researches are in …

[图书][B] Kirk-Othmer Concise Encyclopedia of Chemical Technology, 2 Volume Set

Kirk-Othmer - 2007 - books.google.com
This is an easily-accessible two-volume encyclopedia summarizing all the articles in the
main volumes Kirk-Othmer Encyclopedia of Chemical Technology, Fifth Edition organized …