A review of interactions between platinum coordination complexes and ionizing radiation: implications for cancer therapy
EB Douple, RC Richmond - Cisplatin, 1980 - Elsevier
Publisher Summary This chapter reviews the results and their implications for cancer
therapy. The efficacy of cis-dichlorodiammineplatinum (II), or cisplatin (cis-DDP), as a broad …
therapy. The efficacy of cis-dichlorodiammineplatinum (II), or cisplatin (cis-DDP), as a broad …
Cis-diamminedichloroplatinum (II): effects of a representative metal coordination complex on mammalian cells
EB Douple - Pharmacology & therapeutics, 1984 - Elsevier
For many decades the neutral platinum coordination complex cis-diamminedichloroplatinum
(II), cis-DDP, was known as Peyrone's chloride. First synthesized in 1845, a description of its …
(II), cis-DDP, was known as Peyrone's chloride. First synthesized in 1845, a description of its …
The repair of double-strand DNA breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells
D Wlodek, WN Hittelman - Radiation Research, 1987 - meridian.allenpress.com
To better understand the basis for the difference in radiosensitivity between the variant
murine leukemic lymphoblast cell lines L5178Y-R (resistant) and L5178Y-S (sensitive), the …
murine leukemic lymphoblast cell lines L5178Y-R (resistant) and L5178Y-S (sensitive), the …
Intracellular iron status as a hallmark of mammalian cell susceptibility to oxidative stress: a study of L5178Y mouse lymphoma cell lines differentially sensitive to H2O2
P Lipinski, JC Drapier, L Oliveira… - Blood, The Journal …, 2000 - ashpublications.org
The redox properties of iron make this metal a key participant in oxygen-mediated toxicity.
Accordingly, L5178Y (LY) mouse lymphoma cell lines, which display a unique inverse cross …
Accordingly, L5178Y (LY) mouse lymphoma cell lines, which display a unique inverse cross …
Loss of Tumorigenicity with Simultaneous Changes in Radiosensitivity and Photosensitivity during in Vitro Growth of L5178Y Murine Lymphoma Cells
JZ Beer, E Budzicka, E Niepokojczycka, O Rosiek… - Cancer Research, 1983 - AACR
Murine leukemic lymphoblasts L5178Y-R (LY-R) undergo conversion into their L5178Y-S
(LY-S) variant as a result of prolonged (5 months to 4 years) cultivation in vitro. LY-R cells …
(LY-S) variant as a result of prolonged (5 months to 4 years) cultivation in vitro. LY-R cells …
DNA strand breakage, cytotoxicity and mutagenicity of hydrogen peroxide treatment at 4 C and 37 C in L5178Y sublines
M Kruszewski, MHL Green, JE Lowe… - … and Molecular Mechanisms …, 1994 - Elsevier
Cells from the L5178Y murine lymphoma subline LY-R are twofold more resistant to killing
by ionizing radiation than the subline LY-S. In contrast, LY-R cells are more sensitive to …
by ionizing radiation than the subline LY-S. In contrast, LY-R cells are more sensitive to …
The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells: I. Initial damage
D Wlodek, WN Hittelman - Radiation research, 1988 - meridian.allenpress.com
We investigated the role of initial DNA and chromosome damage in determining the
radiosensitivity difference between the variant murine leukemic lymphoblast cell lines …
radiosensitivity difference between the variant murine leukemic lymphoblast cell lines …
[PDF][PDF] Labile iron pool correlates with iron content in the nucleus and the formation of oxidative DNA damage in mouse lymphoma L5178Y cell lines.
M Kruszewski, T Iwaneńko - Acta Biochimica Polonica, 2003 - bibliotekanauki.pl
Labile iron pool (LIP) constitutes a crossroad of metabolic pathways of iron-containing
compounds and is midway between the cellular need for iron, its uptake and storage. In this …
compounds and is midway between the cellular need for iron, its uptake and storage. In this …
Induction of iron regulatory protein 1 RNA-binding activity by nitric oxide is associated with a concomitant increase in the labile iron pool: implications for DNA damage
P Lipinski, RR Starzynski, JC Drapier, C Bouton… - Biochemical and …, 2005 - Elsevier
Iron regulatory protein 1 (IRP1) is a bifunctional [4Fe–4S] protein that controls iron
homeostasis. Switching off its function from an aconitase to an apo-IRP1 interacting with iron …
homeostasis. Switching off its function from an aconitase to an apo-IRP1 interacting with iron …
The contribution of women to radiobiology: Marie Curie and beyond
A Gasinska - Reports of practical oncology and radiotherapy, 2016 - journals.viamedica.pl
Abstract Marie Sklodowska-Curie, an extraordinary woman, a Polish scientist who lived and
worked in France, led to the development of nuclear energy and the treatment of cancer …
worked in France, led to the development of nuclear energy and the treatment of cancer …