New photosensitizers for photodynamic therapy

H Abrahamse, MR Hamblin - Biochemical Journal, 2016 - portlandpress.com
Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since
become a well-studied therapy for cancer and various non-malignant diseases including …

Comprehensive review of photophysical parameters (ε, Φf, τs) of tetraphenylporphyrin (H2TPP) and zinc tetraphenylporphyrin (ZnTPP)–Critical benchmark molecules …

M Taniguchi, JS Lindsey, DF Bocian… - Journal of Photochemistry …, 2021 - Elsevier
Tetraphenylporphyrin (H 2 TPP) and zinc tetraphenylporphyrin (ZnTPP) are widely used
benchmark molecules in diverse photochemical studies given facile synthetic access, rich …

Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics

S Singh, A Aggarwal, NVSDK Bhupathiraju… - Chemical …, 2015 - ACS Publications
As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …

Recent advances in porphyrin-based MOFs for cancer therapy and diagnosis therapy

Z Wang, Q Sun, B Liu, Y Kuang, A Gulzar, F He… - Coordination Chemistry …, 2021 - Elsevier
Porphyrins and porphyrin derivatives have attracted significant interest in the fields of
catalysis, biosensing, gas storage, solar cells, and biomedical applications owing to their …

Trends and targets in antiviral phototherapy

A Wiehe, JM O'Brien, MO Senge - Photochemical & Photobiological …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

[HTML][HTML] Photodynamic therapy: current status and future directions

L Benov - Medical principles and practice, 2015 - karger.com
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality used for the
management of a variety of cancers and benign diseases. The destruction of unwanted cells …

Synthetic chlorins, possible surrogates for chlorophylls, prepared by derivatization of porphyrins

M Taniguchi, JS Lindsey - Chemical reviews, 2017 - ACS Publications
Chlorophylls make Earth green, are the central constituents in the engine of photosynthesis,
and not surprisingly have garnered immense attention. A chlorin, the core chromophore of a …

[HTML][HTML] New photodynamic therapy with next-generation photosensitizers

H Kataoka, H Nishie, N Hayashi, M Tanaka… - Annals of …, 2017 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a non-invasive antitumor treatment that uses the
combination of a photosensitizer, tissue oxygen, and visible light irradiation to produce …

Antimicrobial photosensitizers: drug discovery under the spotlight

R Yin, M R. Hamblin - Current medicinal chemistry, 2015 - benthamdirect.com
Although photodynamic therapy (PDT) was discovered over a hundred years ago by its
ability to destroy microorganisms, it has been developed mainly as a cancer therapy. In …

Thionated organic compounds as emerging heavy-atom-free photodynamic therapy agents

LA Ortiz-Rodríguez, CE Crespo-Hernández - Chemical Science, 2020 - pubs.rsc.org
This minireview focuses on recent progress in developing heavy-atom-free photosensitizers
based on the thionation of nucleic acid derivatives and other biocompatible organic …