Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia
Kraepelin, in his early descriptions of schizophrenia (SZ), characterized the illness as having
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …
An overview of artificial intelligence techniques for diagnosis of Schizophrenia based on magnetic resonance imaging modalities: Methods, challenges, and future …
Schizophrenia (SZ) is a mental disorder that typically emerges in late adolescence or early
adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior …
adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior …
Neuroinflammation in schizophrenia: the role of nuclear factor kappa B
Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a
subset of people with schizophrenia, with significant increases in inflammatory markers …
subset of people with schizophrenia, with significant increases in inflammatory markers …
Effects of anodal transcranial direct current stimulation on working memory: a systematic review and meta-analysis of findings from healthy and neuropsychiatric …
Background Several studies have trialled anodal transcranial direct current stimulation (a-
tDCS) for the enhancement of working memory (WM) in both healthy and neuropsychiatric …
tDCS) for the enhancement of working memory (WM) in both healthy and neuropsychiatric …
Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder
Importance Prior studies have demonstrated reduced dendritic spine density in the
dorsolateral prefrontal cortex (DLPFC) in schizophrenia. However, it remains unclear how …
dorsolateral prefrontal cortex (DLPFC) in schizophrenia. However, it remains unclear how …
Brain-wide analysis of functional connectivity in first-episode and chronic stages of schizophrenia
Published reports of functional abnormalities in schizophrenia remain divergent due to lack
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
Neural primacy of the salience processing system in schizophrenia
For effective information processing, two large-scale distributed neural networks appear to
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex …
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex …
Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion
Cognitive impairment is a feature of many psychiatric diseases, including schizophrenia.
Here we aim to identify multimodal biomarkers for quantifying and predicting cognitive …
Here we aim to identify multimodal biomarkers for quantifying and predicting cognitive …
Predictive waves in the autism-schizophrenia continuum: a novel biobehavioral model
The brain is a predictive machine. Converging data suggests a diametric predictive strategy
from autism spectrum disorders (ASD) to schizophrenic spectrum disorders (SSD). Whereas …
from autism spectrum disorders (ASD) to schizophrenic spectrum disorders (SSD). Whereas …
The MCIC collection: a shared repository of multi-modal, multi-site brain image data from a clinical investigation of schizophrenia
Expertly collected, well-curated data sets consisting of comprehensive clinical
characterization and raw structural, functional and diffusion-weighted DICOM images in …
characterization and raw structural, functional and diffusion-weighted DICOM images in …