Long non-coding RNA MIR4435-2HG: a key molecule in progression of cancer and non-cancerous disorders

M Ghasemian, M Rajabibazl, U Sahebi… - Cancer Cell …, 2022 - Springer
Abstract MIR4435-2HG (LINC00978) is a long non-coding RNA (lncRNA) that acts as an
oncogene in almost all cancers. This lncRNA participates in the molecular cascades …

Heterogeneity of colorectal cancer progression: molecular gas and brakes

F Gaiani, F Marchesi, F Negri, L Greco… - International journal of …, 2021 - mdpi.com
The review begins with molecular genetics, which hit the field unveiling the involvement of
oncogenes and tumor suppressor genes in the pathogenesis of colorectal cancer (CRC) …

Knockdown of lncRNA LINC01234 Suppresses the Tumorigenesis of Liver Cancer via Sponging miR-513a-5p

W Xu, K Li, C Song, X Wang, Y Li, B Xu, X Liang… - Frontiers in …, 2020 - frontiersin.org
Background Liver cancer is a frequent malignancy with poor prognosis and high mortality all
over the world. It has been reported many lncRNAs could modulate the tumorigenesis of …

The ubiquitin-proteasome system participates in sperm surface subproteome remodeling during boar sperm capacitation

M Zigo, K Kerns, P Sutovsky - Biomolecules, 2023 - mdpi.com
Sperm capacitation is a complex process endowing biological and biochemical changes to
a spermatozoon for a successful encounter with an oocyte. The present study focused on the …

Potential serum metabolites and long‐chain noncoding RNA biomarkers for endometrial cancer tissue

C Hao, S Lin, P Liu, W Liang, Z Li… - Journal of Obstetrics and …, 2023 - Wiley Online Library
Background Endometrial carcinoma (EC) is one of the most common tumors in the female
reproductive system. There are nearly 200 000 new cases every year. It is the third most …

Correlated downregulation of VDR and CYP3A4 in colorectal cancer

H Sadeghi, V Hashemnia… - Molecular Biology …, 2023 - Springer
Background The evidence obtained from experimental studies suggests the tumor-
suppressive effects of vitamin D by controlling the differentiation, proliferation, and apoptosis …

[HTML][HTML] Prognostic prediction and gene regulation network of EIF2S2 in hepatocellular carcinoma based on data mining

P Ji, H Wang, Y Cheng, S Liang - Journal of gastrointestinal …, 2021 - ncbi.nlm.nih.gov
Background Hepatocellular carcinoma (HCC) is a malignant tumor with a high fatality rate,
predicting poor prognosis and therapeutic effect. Screening potential prognostic genes in …

Tracing vitamins on the long non-coding lane of the transcriptome: vitamin regulation of LncRNAs

F Yazarlou, F Alizadeh, L Lipovich, R Giordo… - Genes & nutrition, 2024 - Springer
A major revelation of genome-scale biological studies in the post-genomic era has been that
two-thirds of human genes do not encode proteins. The majority of non-coding RNA …

The implication of TET1, miR-200, and miR-494 expression with tumor formation in colorectal cancer: through targeting Wnt signaling

R Tajali, N Zali, F Naderi Noukabadi, M Jalili… - Molecular Biology …, 2024 - Springer
Objective Colorectal cancer (CRC) is a diverse and multifaceted disease characterized by
genetic and epigenetic changes that contribute to tumor initiation and progression. CRC …

A newly identified lncBCAS1-4_1 associated with vitamin D signaling and EMT in ovarian cancer cells

Y Xue, P Wang, F Jiang, J Yu, H Ding, Z Zhang… - Frontiers in …, 2021 - frontiersin.org
Long noncoding RNAs (lncRNAs) were identified rapidly due to their important role in many
biological processes and human diseases including cancer. 1α, 25-dihydroxyvitamin D3 [1α …