International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

M Sharma, D Leung, M Momenilandi… - Journal of Experimental …, 2023 - rupress.org
STAT6 (signal transducer and activator of transcription 6) is a transcription factor that plays a
central role in the pathophysiology of allergic inflammation. We have identified 16 patients …

Rhinitis associated with asthma is distinct from rhinitis alone: the ARIA‐MeDALL hypothesis

J Bousquet, E Melén, T Haahtela, GH Koppelman… - Allergy, 2023 - Wiley Online Library
Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

Functions and regulation of T cell-derived interleukin-10

C Neumann, A Scheffold, S Rutz - Seminars in immunology, 2019 - Elsevier
Abstract Interleukin (IL)-10 is an essential anti-inflammatory cytokine and functions as a
negative regulator of immune responses to microbial antigens. IL-10 is particularly important …

Recent developments and highlights in allergic rhinitis

Y Meng, C Wang, L Zhang - Allergy, 2019 - Wiley Online Library
Allergic rhinitis (AR) is a disease with high prevalence all over the world and therefore
needs to be thoroughly investigated and treated accordingly. The mechanisms underlying …

Epidemiology of brain and other CNS tumors

QT Ostrom, SS Francis, JS Barnholtz-Sloan - Current neurology and …, 2021 - Springer
Abstract Purpose of Review Brain and other central nervous system (CNS) tumors, while
rare, cause significant morbidity and mortality across all ages. This article summarizes the …

Allergic rhinitis

J Bousquet, JM Anto, C Bachert, I Baiardini… - Nature Reviews …, 2020 - nature.com
Allergic rhinitis (AR) is caused by immunoglobulin E (IgE)-mediated reactions to inhaled
allergens and is one of the most common chronic conditions globally. AR often co-occurs …

Genetics and epigenetics in allergic rhinitis

BY Choi, M Han, JW Kwak, TH Kim - Genes, 2021 - mdpi.com
The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

Omics technologies in allergy and asthma research: An EAACI position paper

U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …