Bipolar disorder (BD) is a mood disorder with subtypes characterized by episodes of mania,
hypomania, and/or depression. BD is associated with substantial economic burden, and the …

OBJECTIVE: To design a functional, patient-centered model of patient complexity with
practical applicability to analytic design and clinical practice. Existing literature on patient …

Background Bipolar disorder is characterized by debilitating episodes of depression and
mood elevation (mania or hypomania). For most patients, depressive symptoms are more …

Background Functional impairment contributes to significant disability and economic burden
in major depressive disorder (MDD). Treatment response is measured by improvement in …

Background Little is known about physical activity and sedentary behavior of adults with
bipolar disorder (BP). Physical activity and sedentary behaviors may be modifiable factors …

Background To identify changes in brain activation patterns in bipolar disorder (BD) and
unipolar depression (UD) patients. Methodology/Principal Findings Resting-state fMRI scans …

Background and objective Caused by shared genetic risk factors and similar
neuropsychological symptoms, bipolar disorder (BD) and major depressive disorder (MDD) …

Objective Epilepsy can reduce quality of life (QOL), functionality, and social participation, but
these effects have not been adequately quantified in large, population-based, controlled …

Objective: Many patients with major depressive disorder (MDD) or bipolar disorder (BD)
experience impairments in daily life. We investigated whether patients with single-episode …

Objective: To investigate distinguishing features between bipolar I, II and unipolar
depression, and impulsivity/aggression traits in particular. Methods: Six hundred and eighty …